Tetrabutylthiuram disulfide

Base Information

• Chemical Name: Tetrabutylthiuram disulfide
• CAS No.: 1634-02-2
• Deprecated CAS: 777902-92-8,1421681-46-0
• Molecular Formula: C18H36N2S4
• Molecular Weight: 408.761
• European Community (EC) Number: 216-652-6
• NSC Number: 677476
• UNII: D969886EAB
• DSSTox Substance ID: DTXSID6049226
• Nikkaji Number: J141.892K
• Wikidata: Q27276262
• ChEMBL ID: CHEMBL333177
• Mol file: 1634-02-2.mol

Synonyms:Tetrabutylthiuram disulfide;1634-02-2;TETRA-N-BUTYLTHIURAM DISULFIDE;Tetrabutylthiuram disulphide;Thiuram disulfide tetrabutyl;Zinc ionophore I;DISULFIDE, BIS(DIBUTYLTHIOCARBAMOYL);dibutylcarbamothioylsulfanyl N,N-dibutylcarbamodithioate;Thiuram, tetrabutyl-, disulfide;Tetrabutylthioperoxydicarbamic acid;NSC 677476;Bis(dibutylthiocarbamoyl) disulfide;EINECS 216-652-6;BRN 1715575;UNII-D969886EAB;CHEMBL333177;DTXSID6049226;D969886EAB;NSC-67746;NSC677476;NSC-677476;Thioperoxydicarbonic diamide, tetrabutyl-;Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetrabutyl-;Thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N',N'-tetrabutyl-;Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N',N'-tetrabutyl-;4-04-00-00595 (Beilstein Handbook Reference);Thioperoxydicarbonic diamide ([(H2N)c(S)]2S2), tetrabutyl-;Methanethioamide, 1,1'-dithiobis[N,N-dibutyl-;METHANETHIOAMIDE, 1,1'-DITHIOBIS(N,N-DIBUTYL-;Butyl tuads;SCHEMBL24804;DTXCID2029082;C18H36N2S4;Bis-(dibutylthiocarbamoyl) disulfide;Tox21_202809;BDBM50570514;MFCD00027191;Tetra-n-butylthiuram disulfide, 98%;AKOS015839733;C18-H36-N2-S4;Tetrabutyl thioperoxydicarbonic diamide;NCGC00260355-01;LS-63041;CAS-1634-02-2;T0635;E78822;J-010042;Zinc ionophore I, Selectophore(TM), function tested;Q27276262;Thioperoxydicarbonic diamide (((H2-N)C(S))2-S2), tetrabutyl-;THIOPEROXYDICARBONIC DIAMIDE (((H2N)C(S))2S2), N,N,N',N'- TETRABUTYL-

Chemical Property of Tetrabutylthiuram disulfide

Chemical Property:

• Vapor Pressure: 2.57E-09mmHg at 25°C
• Melting Point: 95 °C
• Refractive Index: 1.566
• Boiling Point: 478.5 °C at 760 mmHg
• PKA: 0.90±0.50(Predicted)
• Flash Point: 243.2 °C
• PSA: 121.26000
• Density: 1.081 g/cm³
• LogP: 6.74200
• Sensitive.: Air Sensitive
• Water Solubility.: 140μg/L at 25℃
• XLogP3: 7.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 15
• Exact Mass: 408.17613385
• Heavy Atom Count: 24
• Complexity: 289

Purity/Quality:

98% ^*data from raw suppliers

Tetra-n-butylthiuram Disulfide ^*data from reagent suppliers

Safty Information:

• Statements: 20/22-36/37-43-68
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Plastics & Rubber -> Rubber Additives
• Canonical SMILES: CCCCN(CCCC)C(=S)SSC(=S)N(CCCC)CCCC
• Uses: Tetra-n-butylthiuram Disulfide is a zinc ionophore used in the development and characterization of needle-type ion-selective microsensors. It can also be used as a starting material in the synthetic preparation of S-aryl dithiocarbamates. Vulcanizing and accelerating agent.

Technology Process of Tetrabutylthiuram disulfide

There total 9 articles about Tetrabutylthiuram disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

carbon disulfide (75-15-0,12122-00-8) + dibutylamine (111-92-2) → tetrabutylthiuram Disulfide (1634-02-2)

Guidance literature:

With ammonium cerium (IV) nitrate; oxygen; In tetrahydrofuran; at 20 ℃; for 9h;

DOI:10.1039/c4ra04628e

Reference yield: 98.0%

→ tetrabutylthiuram Disulfide (1634-02-2)

Guidance literature:

Reference yield: 88.0%

sodium dibutyl dithiocarbamate (136-30-1) → tetrabutylthiuram Disulfide (1634-02-2)

Guidance literature:

In water; at 25 ℃; Electrolysis; Flow reactor;

DOI:10.1039/d0gc03336g

upstream raw materials:

carbon disulfide

dibutylamine

N,N-dibutyl dithiocarbamate potassium salt

sodium dibutyl dithiocarbamate

Downstream raw materials:

N,N-dibutylbenzamide

Refernces

• 1、 Xu, Hao-Xing,Zhao, Ze-Run,Patehebieke, Yeersen,Chen, Qian-Qian,Fu, Shun-Guo,Chang, Shuai-Jun,Zhang, Xu-Xu,Zhang, Zhi-Liang,Wang, Xiao. "Continuous-flow step-economical synthesis of thiuram disulfidesviavisible-light photocatalytic aerobic oxidation". supporting information. p. 1280 - 1285. Retrieved 2021/02/26.
• 2、 Chen, Cheng,Li, Jia-Qi,Sun, Le-Yun,Wu, Lin-Yu,Yang, Ke-Wu. "Disulfiram as a potent metallo-β-lactamase inhibitor with dual functional mechanisms". . p. 2755 - 2758. Retrieved 2020/03/17.