N-(4-methylbenzyl)glycine

Base Information

• Chemical Name: N-(4-methylbenzyl)glycine
• CAS No.: 5021-38-5
• Molecular Formula: C14H11 Br N2
• Molecular Weight: 179.2157
• Mol file: 5021-38-5.mol

Synonyms:Quinoxaline,3-(p-bromophenyl)-1,2-dihydro- (7CI,8CI)

Chemical Property of N-(4-methylbenzyl)glycine

Chemical Property:

• Vapor Pressure: 9.8E-05mmHg at 25°C
• Boiling Point: 324.8°Cat760mmHg
• Flash Point: 150.2°C
• Density: 1.13g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-methylbenzyl)glycine

There total 2 articles about N-(4-methylbenzyl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1,2-diamino-benzene (95-54-5) + para-bromophenacyl bromide (99-73-0,132309-76-3) → 3-(4-bromo-phenyl)-1,2-dihydro-quinoxaline (5021-38-5)

Guidance literature:

With sodium acetate; In methanol; for 2h; Heating;

DOI:10.1007/BF01175072

Reference yield:

→ 3-(4-bromo-phenyl)-1,2-dihydro-quinoxaline (5021-38-5)

Guidance literature:

o-Phenylendiamin, 2,4'-Dibrom-acetophenon, Na-acetat/Me.;

Reference yield: 82.0%

3-(4-bromo-phenyl)-1,2-dihydro-quinoxaline (5021-38-5) → 2-(4-bromophenyl)quinoxaline (5021-45-4)

Guidance literature:

With benzofurazan oxide; In acetonitrile; for 0.0833333h;

DOI:10.1080/00397919208021304

upstream raw materials:

1,2-diamino-benzene

para-bromophenacyl bromide

Downstream raw materials:

2-(4-bromophenyl)quinoxaline

Refernces