Sodium;4-amino-5-hydroxy-5-oxopentanoate;hydrate

Base Information Edit

Chemical Name:Sodium;4-amino-5-hydroxy-5-oxopentanoate;hydrate
CAS No.:32221-81-1
Molecular Formula:C5H8NNaO4
Molecular Weight:169.113
Hs Code.:2103901000
European Community (EC) Number:608-719-7
RXCUI:2049260
Mol file:32221-81-1.mol

Synonyms:Monosodium DL-glutamate;32221-81-1;Glutamic acid, monosodium salt, DL-;C5-H8-N-O4.Na;SCHEMBL14485529

Suppliers and Price of Sodium;4-amino-5-hydroxy-5-oxopentanoate;hydrate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Monosodium glutamate United States Pharmacopeia (USP) Reference Standard
500 mg
$ 366.00

Total 130 raw suppliers

Chemical Property of Sodium;4-amino-5-hydroxy-5-oxopentanoate;hydrate Edit

Chemical Property:

Appearance/Colour:white crystalline solid
Boiling Point:333.8 °C at 760 mmHg
Flash Point:155.7 °C
PSA：103.45000
LogP:-1.37130
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:187.04566670
Heavy Atom Count:12
Complexity:149

Purity/Quality:

99.9% ^*data from raw suppliers

Monosodium glutamate United States Pharmacopeia (USP) Reference Standard ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(=O)[O-])C(C(=O)O)N.O.[Na+]
Recent NIPH Clinical Trials:Effect of monosodium glutamate on cognitive function in people with dementia
Description Monosodium glutamate, known as MSG, is the sodium salt of the amino acid glutamic acid present in all protein. It is marketed as a white crystalline salt used to enhance fl avor as the monohydrate, C5H8NNaO4 H2O.There are two forms of glutamic acid: L-glutamic acid and D-glutamic acid. The natural glutamic acid found in humans and other higher organism is L-glutamic acid only, whereas processed monosodium glutamate contains both L-glutamic acid and D-glutamic acid along with pyroglutamic acid (C5H7NO3) and other contaminants. Monosodium glutamate(MSG) is odorless and has little flavor. It works synergistically with other substances found in food proteins such as the nucleotides disodium 5'-inosine monophosphate (IMP) and disodium 5'-guanosine monophosphate (GMP), to produce a pleasing savory taste.
Uses The safety of manufactured Monosodium glutamate(MSG) has been questioned for the last several decades. Conditions associated with Monosodium glutamate(MSG) symptom complex included numbness in the back of the neck, radiating to the arms; warmth and fatigue in the head, upper back, neck, and arms; facial pressure or tightness; chest pain; headache; nausea; and heart palpitations. There does not seem to be an absolute consensus on the safety of MSG, but for the most part Monosodium glutamate(MSG) is considered safe if consumed in normal quantities. An acceptable daily intake level is not cited by government regulators, but the average person consumes between 0.3 and 1.0 gram of Monosodium glutamate(MSG) daily. Estimates of annual global production of Monosodium glutamate(MSG) range between several hundred thousand tons to as high as 1 million tons. Although practically all Monosodium glutamate(MSG) produced is used in the food industry, a small portion is used for agricultural feed supplements (for swine), pesticides, and pharmaceuticals. Monosodium glutamate (MSG) is a flavor enhancer that is the sodium salt of glutamic acid, an amino acid. It is a white crystal that is readily soluble in water. It intensifies and enhances flavor but does not contribute a flavor of its own. It may be present as one of the amino acids or in a free form, which is how it effectively enhances the flavor of foods. It is produced through a fermentation process of molasses. It is used at 0.1–1.0% in meats, soups, and sauces.

Technology Process of Sodium;4-amino-5-hydroxy-5-oxopentanoate;hydrate

There total 4 articles about Sodium;4-amino-5-hydroxy-5-oxopentanoate;hydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 142-47-2
monosodium glutamate

: 32221-81-1
L,D-glutamic acid sodium salt

Guidance literature:: With sodium hydroxide; borate buffer; copper(II) sulfate; pyridoxal; In ethanol; water; at 25 ℃; for 188h; Rate constant; pH= 10.0; other catalysts;
DOI:10.1246/cl.1981.5

Reference yield:

: 98-79-3
L-Pyroglutamic acid

: 142-47-2,149-65-5,15383-53-6,16079-50-8,16177-21-2,16690-92-9,21932-17-2,26247-79-0,28223-73-6,30617-64-2,30811-79-1,32221-81-1,32342-59-9,56-86-0
glutamic acid sodium salt

Guidance literature:: With sodium hydroxide; hydrogen; 5% activated charcoal-supported ruthenium catalyst; In water; at 150 ℃; for 2h; under 103432 Torr;