Dodecylbenzenesulfonyl azide

Base Information

• Chemical Name: Dodecylbenzenesulfonyl azide
• CAS No.: 79791-38-1
• Molecular Formula: C18H29N3O2S
• Molecular Weight: 351.513
• Hs Code.: 29350090
• Mol file: 79791-38-1.mol

Synonyms:4-Dodecylbenzenesulfonylazide;p-Dodecylbenzenesulfonyl azide;

Chemical Property of Dodecylbenzenesulfonyl azide

Chemical Property:

• Melting Point: 108-110°C
• Refractive Index: n20/D1.510
• Flash Point: >110℃
• PSA: 92.27000
• Density: 1.051 g/mL at 25 °C
• LogP: 6.68256
• Solubility.: solubility pentane, acetone, and most organic solvents.

Purity/Quality:

99% ^*data from raw suppliers

Dodecylbenzenesulfonyl azide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 10-36/37/38-20/22
• Safety Statements: 16-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• uses: diazo-transfer reagent for activated methylene groups.
• Uses: Reactant or reagent for synthesis of:Positron emission tomography ligand for imaging metabotropic glutamate receptor type 1Stitching agent for introduction of aziridines into functionalized organic moleculesParenteral cephalosporinsReagent for:Intermolecular metal-catalyzed carbenoid cyclopropanationsSolid-phase synthesis of indolecarboxylates using palladium catalyzed reactionsSolid-phase rhodium carbenoid N-H insertion reactions

Technology Process of Dodecylbenzenesulfonyl azide

There total 2 articles about Dodecylbenzenesulfonyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.2%

p-dodecylbenzenesulfonyl chloride (52499-14-6) → 4-dodecylbenzenesulphonyl azide (79791-38-1)

Guidance literature:

With sodium azide; In water; acetone; at 10 - 30 ℃; Temperature; Flow reactor;

Reference yield:

→ 4-dodecylbenzenesulphonyl azide (79791-38-1)

Guidance literature:

Reference yield: 95.0%

4-nitrobenzyl chloride (619-73-8) + 4-dodecylbenzenesulphonyl azide (79791-38-1) + acetoacetic acid methyl ester (105-45-3) → 4-nitrobenzyl 2-diazo-3-oxo-butanoate (82551-63-1)

Guidance literature:

With triethylamine; In toluene;

upstream raw materials:

p-dodecylbenzenesulfonyl chloride

Downstream raw materials:

butyl 5-(3-buten-1-yl)-1-{4-[(tert-butoxycarbonyl)amino]phenyl}-1H-1,2,3-triazole-4-carboxylate

4-nitrobenzyl 2-diazo-3-oxo-butanoate

(3S,4R)-3-[(R)-1-hydroxyethyl)-4-[3-(4-nitrobenzyl)oxycarbonyl-2-oxo-3-diazopropyl]azetidin-2-one

cis-α-diazo-β,4-dioxo-3-[(phenoxyacetyl)amino]-2-azetidinepentanoic acid, (4-nitrophenyl)methyl ester

Refernces

• 1、 Kang, Taek,Kim, Youngchan,Lee, Donggun,Wang, Zhen,Chang, Sukbok. "Iridium-catalyzed intermolecular amidation of sp3 C-H bonds: Late-stage functionalization of an unactivated methyl group". supporting information. p. 4141 - 4144. Retrieved 2014/04/03.