L-Alanyl-L-alanine

Base Information

• Chemical Name: L-Alanyl-L-alanine
• CAS No.: 2392-61-2
• Molecular Formula: C₆H₁₂N₂O₃
• Molecular Weight: 160.173
• Mol file: 2392-61-2.mol

Synonyms:Alanine,N-L-alanyl-, L- (8CI); L-Alanine, N-L-alanyl-; 124: PN: WO2006024694 SEQID: 124claimed protein; Di-L-alanine; Dialanine; L-Alanyl-L-alanine; NSC 89598; a-Alanylalanine

Chemical Property of L-Alanyl-L-alanine

Chemical Property:

• Vapor Pressure: 1.31E-07mmHg at 25°C
• Melting Point: 286-288 ºC
• Boiling Point: 402.6°C at 760 mmHg
• Flash Point: 197.3°C
• PSA: 92.42000
• Density: 1.208g/cm³
• LogP: 0.01410

Purity/Quality:

99% ^*data from raw suppliers

L-Alanyl-L-alanine United States Pharmacopeia (USP) Reference Standard ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Alanyl-L-alanine

There total 69 articles about L-Alanyl-L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-alanine-L-alanine-p-nitroanilide (57282-69-6,115846-28-1,115846-37-2) → di-L-alanine (1948-31-8,110652-05-6,210687-33-5,2392-61-2) + 4-nitro-aniline (100-01-6,104810-17-5)

Guidance literature:

at 37 ℃; for 0.166667h; 0.1 M Tris HCl buffer pH 8.0, X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis subsp. cremoris nTR;

DOI:10.1271/bbb.56.704

Reference yield:

N-pyruvoyl-alanine (2392-63-4,188300-91-6,877036-29-8) + water (7732-18-5) + phenylglycin (2835-06-5) → DL-α-alanylalanine (1115-78-2,1948-31-8,2867-20-1,3695-80-5,56271-29-5,59247-16-4,90580-65-7,90760-70-6,99265-26-6,923-16-0,110652-05-6,210687-33-5,2392-61-2) + carbon dioxide (124-38-9,18923-20-1) + benzaldehyde (100-52-7)

Guidance literature:

Reference yield:

L-alanin (56-41-7,25191-17-7,18875-37-1) + (S,S)-N,N'-bis(1-carboxyethyl)urea (98337-25-8) → (R)-2-((S)-2-Amino-propionylamino)-propionic acid (3695-80-5,110652-05-6,210687-33-5,2392-61-2) + di-L-alanine (1948-31-8,110652-05-6,210687-33-5,2392-61-2) + L-ala-L-ala-L-ala (5874-90-8)

Guidance literature:

With carbon dioxide; sodium hydrogencarbonate; at 80 ℃; for 840h; pH=7.1;

DOI:10.1021/ja061339+

upstream raw materials:

DL-2-(2-hydroxyimino-propionylamino)-propionic acid

N-(2-bromo-propionyl)-alanine

cyclo(-DL-Ala-DL-Ala-)

AlaOEt

Downstream raw materials:

adenosine 2',3'-cyclic monophosphate

C₁₈H₂₅N₃O₆

D-alanyl-D-alanine methyl ester hydrochloride

(S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanoate

Refernces

• 1、 Klepel, Florian,Ravoo, Bart Jan. "A dynamic combinatorial library for biomimetic recognition of dipeptides in water". supporting information. p. 1588 - 1595. Retrieved 2020/09/16.
• 2、 Fujimoto, Chikako,Shinozaki, Ayako,Mimura, Koichi,Nishida, Tamihito,Gotou, Hirotada,Komatsu, Kazuki,Kagi, Hiroyuki. "Pressure-induced oligomerization of alanine at 25 °C". . p. 13358 - 13361. Retrieved 2015/08/24.