4,4'-Bis(hydroxymethyl)biphenyl

Base Information

• Chemical Name: 4,4'-Bis(hydroxymethyl)biphenyl
• CAS No.: 1667-12-5
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Hs Code.: 2906299090
• Mol file: 1667-12-5.mol

Synonyms:4,4'-Biphenyldimethanol(6CI,7CI,8CI);4,4'-Dimethylol-1,1'-biphenyl;Biphenyl-4,4'-diyldimethanol;[1,1'-Biphenyl]-4,4'-dimethanol;

Chemical Property of 4,4'-Bis(hydroxymethyl)biphenyl

Chemical Property:

• Melting Point: 191-192 °C
• Boiling Point: 416.341 °C at 760 mmHg
• PKA: 14.01±0.10(Predicted)
• Flash Point: 204.517 °C
• PSA: 40.46000
• Density: 1.175 g/cm³
• LogP: 2.33820
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: almost transparency in hot EtOH

Purity/Quality:

99% ^*data from raw suppliers

4,4''-Bis(hydroxymethyl)biphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-Bis(hydroxymethyl)biphenyl

There total 16 articles about 4,4'-Bis(hydroxymethyl)biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.6%

4,4'-biphenyldicarboxylic acid dimethyl ester (792-74-5) → 4,4'-bis(hydroxymethyl)biphenyl (1667-12-5)

Guidance literature:

With LiAlH₄; In tetrahydrofuran; tetrahydrofuran-water; acetone;

Reference yield: 96.6%

4,4'-biphenyldicarboxylic acid dimethyl ester (792-74-5) + water (7732-18-5) → 4,4'-bis(hydroxymethyl)biphenyl (1667-12-5)

Guidance literature:

With LiAlH₄; In tetrahydrofuran; ethanol; acetone;

Reference yield: 96.0%

4,4'-bis(acetoxymethyl)biphenyl (3883-85-0) → 4,4'-bis(hydroxymethyl)biphenyl (1667-12-5)

Guidance literature:

With potassium hydroxide; In methanol; water; for 8h; Heating;

DOI:10.1081/SCC-200048397

upstream raw materials:

4,4'-bis(acetoxymethyl)biphenyl

N,N'-dimethyl-N,N'-diphenyl-biphenyl-4,4'-dicarboxamide

4,4'-diphenic acid

4,4'-bis(chloromethyl)biphenyl

Downstream raw materials:

C₃₀H₂₂O₄

(2E,2′E)-3,3′-([1,1′-biphenyl]-4,4′-diyl)bis(1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one)

C₃₀H₂₂O₂

4,4'-di((E)-styryl)-1,1'-biphenyl

Refernces

• 1、 Valiente, Alejandro,Carrasco, Sergio,Sanz-Marco, Amparo,Tai, Cheuk-Wai,Bermejo Gómez, Antonio,Martín-Matute, Belén. "Aerobic Homocoupling of Arylboronic Acids Catalyzed by Regenerable Pd(II)@MIL-88B-NH2(Cr)". . p. 3933 - 3940. Retrieved 2019/05/22.
• 2、 Gurung, Santosh K.,Kim, Soo Bae,Park, Haeil. "Synthesis and characterization of novel unnatural bichalcones". experimental part. p. 1919 - 1926. Retrieved 2012/01/05.