(S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate

Base Information Edit

Chemical Name:(S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate
CAS No.:1289646-78-1
Molecular Formula:C₂₂H₂₇NO₆S
Molecular Weight:433.525
Hs Code.:
Mol file:1289646-78-1.mol

Synonyms:(S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate

Suppliers and Price of (S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
N-Boc-3-(methylsulfonyl)-L-phenylalanineBenzylEster 95%
1g
$ 574.00

AK Scientific
N-Boc-3-(methylsulfonyl)-L-phenylalanineBenzylEster
1g
$ 937.00

Activate Scientific
N-Boc-3-(methylsulfonyl)-L-phenylalanine Benzyl Ester 95+%
1 g
$ 669.00

Total 3 raw suppliers

Chemical Property of (S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate Edit

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

N-Boc-3-(methylsulfonyl)-L-phenylalanineBenzylEster 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate

There total 4 articles about (S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1289646-76-9
(S)-2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propanol

: 100-51-6,185532-71-2
benzyl alcohol

: 1289646-78-1
(S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;

Reference yield:

: 82311-69-1,99295-78-0
(S)-2-amino-3-(3-bromophenyl)propanoic acid

: 1289646-78-1
(S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / 1,4-dioxane; water / 20 °C

2: copper(l) iodide; caesium carbonate; L-proline / dimethyl sulfoxide / 9 h / 100 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C

With dmap; copper(l) iodide; sodium hydrogencarbonate; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; L-proline; In 1,4-dioxane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/ml2002482

Reference yield:

: 82278-73-7
(2S)-3-(3-bromophenyl)-2-[(tert-butoxycarbonyl)amino]propanoic acid

: 1289646-78-1
(S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-((3-methylsulfonyl)phenyl)propionate

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; caesium carbonate; L-proline / dimethyl sulfoxide / 9 h / 100 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C

With dmap; copper(l) iodide; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; L-proline; In dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/ml2002482