(R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine

Base Information Edit

Chemical Name:(R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine
CAS No.:121216-43-1
Molecular Formula:C₁₁H₁₅NO
Molecular Weight:177.246
Hs Code.:
DSSTox Substance ID:DTXSID40563624
Nikkaji Number:J1.311.133B
Wikidata:Q72439021
Mol file:121216-43-1.mol

Synonyms:121216-43-1;(R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine;(R)-7-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINE;(2R)-7-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine;(R)-(+)-7-METHOXY 2-AMINOTETRALIN;(R)-2-AMINO-7-METHOXYTETRALIN;SCHEMBL354006;DTXSID40563624;ZNWNWWLWFCCREO-SNVBAGLBSA-N;AMY25545;AKOS006273961;PD039886;CS-0442484;EN300-330142;A891840

Suppliers and Price of (R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
(R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine 96%
50mg
$ 156.00

Crysdot
(R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine 95+%
1g
$ 595.00

Chemenu
(R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine 95%
1g
$ 557.00

American Custom Chemicals Corporation
(R)-(+)-7-METHOXY 2-AMINOTETRALIN 95.00%
5MG
$ 505.00

Alichem
(R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine
1g
$ 480.00

Total 18 raw suppliers

Chemical Property of (R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine Edit

Chemical Property:

Vapor Pressure:0.00118mmHg at 25°C
Refractive Index:1.547
Boiling Point:299.6 °C at 760 mmHg
Flash Point:139.7 °C
PSA：35.25000
Density:1.056 g/cm³
LogP:2.21150
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:177.115364102
Heavy Atom Count:13
Complexity:172

Purity/Quality:

98%min ^*data from raw suppliers

(R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(CCC(C2)N)C=C1
Isomeric SMILES:COC1=CC2=C(CC[C@H](C2)N)C=C1

Technology Process of (R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine

There total 8 articles about (R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4003-89-8,118298-16-1
2-amino-7-methoxy-1,2,3,4-tetrahydronaphthalene

: 121216-43-1,118298-16-1
(2R)-7-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine

Guidance literature:: DOI:10.1016/0223-5234(94)90095-7

Reference yield:

: 4133-34-0
7-methoxyl-2-tetralone

: 121216-43-1,118298-16-1
(2R)-7-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine

Guidance literature:: Multi-step reaction with 5 steps

1.1: dichloromethane / 0.25 h / Inert atmosphere

1.2: 15 h / 20 °C / Inert atmosphere

2.1: 20 % Pd(OH)2/C; hydrogen; acetic acid / ethanol / 24.08 h / 20 °C

3.1: sodium hydroxide / water; ethyl acetate

4.1: methanol; water; isopropyl alcohol; toluene / 0.5 h / Reflux

5.1: sodium hydroxide / water; ethyl acetate

With 20 % Pd(OH)2/C; hydrogen; acetic acid; sodium hydroxide; In methanol; ethanol; dichloromethane; water; ethyl acetate; isopropyl alcohol; toluene;
DOI:10.1021/jm101479y