2-(4-hydroxyphenyl)-5-pentylthiophene

Base Information

• Chemical Name: 2-(4-hydroxyphenyl)-5-pentylthiophene
• CAS No.: 117694-81-2
• Molecular Formula: C₁₅H₁₈OS
• Molecular Weight: 246.373
• Mol file: 117694-81-2.mol

Synonyms:2-(4-hydroxyphenyl)-5-pentylthiophene

Chemical Property of 2-(4-hydroxyphenyl)-5-pentylthiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-hydroxyphenyl)-5-pentylthiophene

There total 4 articles about 2-(4-hydroxyphenyl)-5-pentylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-pentyl-thiophene (4861-58-9) → 2-(4-hydroxyphenyl)-5-pentylthiophene (117694-81-2)

Guidance literature:

Multi-step reaction with 4 steps

1: NBS; acetic acid / CHCl₃

2: Na₂CO₃ / Pd(PPh₃)4 / 1,2-dimethoxy-ethane; H₂O

3: boron tribromide / CH₂Cl₂

4: H₃O⁽¹⁺⁾

With N-Bromosuccinimide; oxonium; boron tribromide; sodium carbonate; acetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; dichloromethane; chloroform; water; 2: Suzuki coupling;

DOI:10.1080/10587250108025061

Reference yield:

2-bromo-5-pentylthiophene (301199-32-6) → 2-(4-hydroxyphenyl)-5-pentylthiophene (117694-81-2)

Guidance literature:

Multi-step reaction with 3 steps

1: Na₂CO₃ / Pd(PPh₃)4 / 1,2-dimethoxy-ethane; H₂O

2: boron tribromide / CH₂Cl₂

3: H₃O⁽¹⁺⁾

With oxonium; boron tribromide; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; dichloromethane; water; 1: Suzuki coupling;

DOI:10.1080/10587250108025061

Reference yield:

2-(4-methoxyphenyl)-5-pentylthiophene (301199-35-9) → 2-(4-hydroxyphenyl)-5-pentylthiophene (117694-81-2)

Guidance literature:

With boron tribromide;

DOI:10.1039/b202073b

upstream raw materials:

2-(4-methoxyphenyl)-5-pentylthiophene

2-pentyl-thiophene

2-bromo-5-pentylthiophene

Downstream raw materials:

2-(4-[(E)-hex-2-enyloxy]phenyl)-5-pentylthiophene

Refernces

• 1、 Bartle, Kevin,Campbell, Neil,Duffy, Warren L.,Kelly, Stephen M.,Minter, Vicki,O'Neill, Mary,Tuffin, Rachel P.. "Nematic thiophenes for STN-LCDS and flexoelectric LCDS". . p. 881 - 888. Retrieved 2007/10/03.