(E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate

Base Information

• Chemical Name: (E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate
• CAS No.: 1028098-06-7
• Molecular Formula: C₃₀H₂₉O₆P
• Molecular Weight: 516.53
• Mol file: 1028098-06-7.mol

Synonyms:(E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate

Chemical Property of (E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate

There total 3 articles about (E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3,5-dimethoxy-4'-hydroxy-trans-stilbene (537-42-8,18259-15-9) + dibenzyl phosphochloridate (538-37-4) → (E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate (1028098-06-7)

Guidance literature:

With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

Reference yield: 80.0%

Dibenzyl phosphite (17176-77-1) + 3,5-dimethoxy-4'-hydroxy-trans-stilbene (537-42-8,18259-15-9) → (E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate (1028098-06-7)

Guidance literature:

With tetrachloromethane; dmap; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 12h;

DOI:10.1016/j.bmc.2008.01.051

Reference yield:

3,5-dimethoxy-4'-hydroxy-trans-stilbene (537-42-8,18259-15-9) + phosphoric acid dibenzyl ester (1623-08-1) → (E)-dibenzyl 4-(3,5-dimethoxystyryl)phenyl phosphate (1028098-06-7)

Guidance literature:

3,5-dimethoxy-4'-hydroxy-trans-stilbene; With tetrachloromethane; dmap; N-ethyl-N,N-diisopropylamine; In acetonitrile; at -10 ℃; for 0.5h;

phosphoric acid dibenzyl ester; In acetonitrile; at 20 ℃; for 12h;

upstream raw materials:

Dibenzyl phosphite

3,5-dimethoxy-4'-hydroxy-trans-stilbene

phosphoric acid dibenzyl ester

dibenzyl phosphochloridate

Downstream raw materials:

(E)-4-(3,5-dimethoxystyryl)phenyl dihydrogen phosphate

Refernces

• 1、 -. "A phosphoric acid ester [...] synthesis method of disodium salt". Paragraph 0031-0032. . Retrieved 2017/03/08.
• 2、 -. "PREVENTION AND TREATMENT OF COLON CANCER". Page/Page column 27-28. . Retrieved 2008/12/06.