S-(4-nitrophenyl) thioformate

Base Information

• Chemical Name: S-(4-nitrophenyl) thioformate
• CAS No.: 27064-04-6
• Molecular Formula: C₇H₅NO₃S
• Molecular Weight: 183.188
• Mol file: 27064-04-6.mol

Synonyms:S-(4-nitrophenyl) thioformate

Chemical Property of S-(4-nitrophenyl) thioformate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-(4-nitrophenyl) thioformate

There total 2 articles about S-(4-nitrophenyl) thioformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

formic acid (64-18-6) + para-nitrobenzenethiol (1849-36-1) → S-(4-nitrophenyl) thioformate (27064-04-6)

Guidance literature:

formic acid; With acetic anhydride; at 45 ℃; for 2.5h; Schlenk technique;

para-nitrobenzenethiol; With pyridine; at 30 ℃; for 24h;

DOI:10.1002/ejoc.201701753

Reference yield:

para-nitrobenzenethiol (1849-36-1) + formyl acetic anhydride (2258-42-6) → S-(4-nitrophenyl) thioformate (27064-04-6)

Guidance literature:

DOI:10.1021/ja00528a040

Reference yield: 98.0%

S-(4-nitrophenyl) thioformate (27064-04-6) + C9H9BrZn*LiCl → (E)-2-methylcinnamaldehyde (4549-82-0,93614-78-9)

Guidance literature:

With tris(3,5-difluorophenyl)phosphine; palladium diacetate; zinc dibromide; In tetrahydrofuran; at -20 ℃; for 0.166667h; Schlenk technique;

DOI:10.1002/ejoc.201701753

upstream raw materials:

para-nitrobenzenethiol

formyl acetic anhydride

formic acid

Downstream raw materials:

formohydroxamic acid

formate

4-nitrophenylthiolate

2-methyl-2-phenyl-but-3-enal

Refernces

• 1、 Pohl, Eric R.,Wu, Dorothy,Hupe, D.J.. "Effect of Solvation on β-Values of Formyl Acetyl, and Pivaloyl Transfer between Sulfur and Oxygen Nucleophiles". . p. 2759 - 2763. Retrieved 2007/10/02.