Technology Process of (+/-)-leucoperezone trimethyl ether
There total 15 articles about (+/-)-leucoperezone trimethyl ether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylsilane; boron trifluoride diethyl etherate;
In
dichloromethane;
at -78 ℃;
for 0.5h;
DOI:10.1016/S0040-4020(01)96630-X
- Guidance literature:
-
With
triethylsilane; boron trifluoride diethyl etherate;
In
dichloromethane;
for 2h;
Inert atmosphere;
Reflux;
DOI:10.1002/anie.201911978
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 82 percent / 90percent HNO3 / 0.17 h / -10 °C
2: 95 percent / H2 / 10percent palladized charcoal / methanol / 586 Torr / Ambient temperature
3: 70 percent / NaNO2 / aq. H2SO4 / 0.25 h / Ambient temperature; 50 deg C, 30 min
4: 82 percent / anhydrous potassium carbonate / acetone / 5 h / Heating
5: 1.) 1.6 M n-butyllithium / 1.) ethyl ether, hexane, 0 deg C, 30 min then room temperature; 2.) 0 deg C, 30 min
6: 82 percent / triethyl silane, boron trifluoride etherate / CH2Cl2 / 0.5 h / -78 °C
With
triethylsilane; n-butyllithium; boron trifluoride diethyl etherate; hydrogen; nitric acid; potassium carbonate; sodium nitrite;
palladium on activated charcoal;
In
methanol; dichloromethane; sulfuric acid; acetone;
DOI:10.1016/S0040-4020(01)96630-X
