pantolactone p-nitrobenzoate

Base Information

• Chemical Name: pantolactone p-nitrobenzoate
• CAS No.: 134734-33-1
• Molecular Formula: C₁₃H₁₃NO₆
• Molecular Weight: 279.249
• Mol file: 134734-33-1.mol

Synonyms:pantolactone p-nitrobenzoate

Chemical Property of pantolactone p-nitrobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of pantolactone p-nitrobenzoate

There total 12 articles about pantolactone p-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

p-nitrobenzoate of 4-hydroxy-5-methoxy-3,3-dimethyltetrahydrofuran (134734-30-8) → pantolactone p-nitrobenzoate (134734-33-1)

Guidance literature:

With boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 3h; Ambient temperature;

DOI:10.1002/jhet.5570280315

Reference yield:

4-nitro-benzoyl chloride (122-04-3) + pantolactone (79-50-5) → pantolactone p-nitrobenzoate (134734-33-1)

Guidance literature:

With pyridine;

DOI:10.1021/ja01864a037 DOI:10.1672/0277-5212(2002)022[0149:SRPTAW]2.0.CO;2

Reference yield:

pantolactone (79-50-5) → O-(4-nitro-benzoyl)-L-pantolactone (134734-33-1)

Guidance literature:

Multi-step reaction with 2 steps

1: quinine

2: pyridine

With pyridine; Quinine;

DOI:10.1021/ja01864a037

upstream raw materials:

4-nitro-benzoyl chloride

(S)-pantolactone

pantolactone

(R)-Pantolacton

Downstream raw materials:

pantolactone

Refernces

• 1、 Kinoshita,Hirano,Miyake. "Synthesis of (±)-pantolactone and (±)-dihydro-4-ethyl-3-hydroxy-4-methyl-2(3H)furanone". . p. 619 - 624. Retrieved 2007/10/02.