1,12-Dimethoxydodecane

Base Information

• Chemical Name: 1,12-Dimethoxydodecane
• CAS No.: 73120-52-2
• Molecular Formula: C14H30 O2
• Molecular Weight: 230.391
• DSSTox Substance ID: DTXSID10474137
• Nikkaji Number: J443.631H
• Wikidata: Q82303944
• Mol file: 73120-52-2.mol

Synonyms:1,12-dimethoxydodecane;Dodecane,1,12-dimethoxy-;73120-52-2;SCHEMBL851363;DTXSID10474137

Chemical Property of 1,12-Dimethoxydodecane

Chemical Property:

• Melting Point: 11.5°C
• Refractive Index: 1.4360 (estimate)
• Boiling Point: 312.39°C (rough estimate)
• PSA: 18.46000
• Density: 0.8563
• LogP: 4.18020
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 13
• Exact Mass: 230.224580195
• Heavy Atom Count: 16
• Complexity: 101

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCCCCCCCCCCCOC

Technology Process of 1,12-Dimethoxydodecane

There total 11 articles about 1,12-Dimethoxydodecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,12-dodecandiol (5675-51-4) + carbonic acid dimethyl ester (616-38-6) → 1,12-dimethoxydodecane (73120-52-2)

Guidance literature:

With tungsten hexacarbonyl; at 180 ℃; for 1h;

DOI:10.1134/S1070428014070057

Reference yield: 34.7%

methanol (67-56-1) + dodecane-1,12-diyl bis(4-methylbenzenesulfonate) (36247-34-4) → 1,12-dimethoxydodecane (73120-52-2)

Guidance literature:

With sodium methylate; Heating;

DOI:10.1021/jo00027a014

Reference yield:

1,5-dibromo-pentane (111-24-0) → 1,7-dimethoxyheptane (137333-33-6) + 1,32-dimethoxy-dotriacontane + hexyl methyl ether (4747-07-3) + 1,12-dimethoxydodecane (73120-52-2)

Guidance literature:

Bei der Grignardierung und behandelt man das Grignardierungsprodukt mit Chlormethylaether;

upstream raw materials:

1,5-dibromo-pentane

1-bromo-6-methoxyhexane

iodo-6 methoxy-1 hexane

chloromethyl methyl ether

Downstream raw materials:

thapsic acid

1,12-diacetoxydodecane

1,12-dodecanedioic acid

1,12-dibromododecane

Refernces

• 1、 Hogan, John C.,Gandour, Richard D.. "Fingerprinting a Transition-Structure Guest by a Building-Block Approach with an Incremental Series of Catalytic Hosts. Structural Requirements for Glyme and α,ω-Dimethoxyalkane Catalyses in N-Methylbutylaminolysis and Butylaminolysis of 4-Nitrophenyl Acetate in Chlorobenzene". . p. 55 - 61. Retrieved 2007/10/02.