(R)-ethyl O-bezenesulfonyl lactate

Base Information

• Chemical Name: (R)-ethyl O-bezenesulfonyl lactate
• CAS No.: 83261-05-6
• Molecular Formula: C₁₁H₁₄O₅S
• Molecular Weight: 258.295
• Mol file: 83261-05-6.mol

Synonyms:(R)-ethyl O-bezenesulfonyl lactate

Chemical Property of (R)-ethyl O-bezenesulfonyl lactate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-ethyl O-bezenesulfonyl lactate

There total 2 articles about (R)-ethyl O-bezenesulfonyl lactate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

(S)-Ethyl lactate (687-47-8) + potassium benzenesulfonate (934-55-4) → (R)-ethyl O-bezenesulfonyl lactate (83261-05-6)

Guidance literature:

potassium benzenesulfonate; With thionyl chloride; In N,N-dimethyl-formamide; toluene; at 0 - 55 ℃; for 3.5h;

(S)-Ethyl lactate; With triethylamine; In N,N-dimethyl-formamide; toluene; at 65 ℃; for 4h;

DOI:10.1021/acs.jced.7b00998

Reference yield:

(S)-Ethyl lactate (687-47-8) + benzenesulfonyl chloride (98-09-9) → (R)-ethyl O-bezenesulfonyl lactate (83261-05-6)

Guidance literature:

With pyridine; at 0 ℃; Yield given;

DOI:10.1002/hlca.19820650413

Reference yield: 89.0%

4-(6-chlorobenzo[d]oxazol-2-yloxy)phenol (70217-01-5) + (R)-ethyl O-bezenesulfonyl lactate (83261-05-6) → fenoxaprop-p-ethyl (66441-23-4,71283-80-2,113776-20-8,116573-18-3,82110-72-3)

Guidance literature:

With potassium carbonate; In cyclohexane; for 12h; Heating / reflux;

upstream raw materials:

(S)-Ethyl lactate

benzenesulfonyl chloride

potassium benzenesulfonate

Downstream raw materials:

L-2-(Benzolsulfonyloxy)propionsaeure

O--aceton-oxim

fenoxaprop-p-ethyl

Refernces

• 1、 Garot, C.,Javed, T.,Mason, T. J.,Turner, J. L.,Cooper, J. W.. "Friedel-Crafts alkylation of aromatic compounds with optically active 2-(mesyloxy)propionates. Synthesis of the optically active anti-inflammatory agent (S)-2-(4-isobutylphenyl)propionic acid". . p. 755 - 758. Retrieved 2007/10/03.