2,3,3,3-Tetrafluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)propan-1-ol

Base Information

• Chemical Name: 2,3,3,3-Tetrafluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)propan-1-ol
• CAS No.: 14548-74-4
• Molecular Formula: C9H3F17O3
• Molecular Weight: 482.094
• Hs Code.: 2906290090
• European Community (EC) Number: 695-661-0
• DSSTox Substance ID: DTXSID80371164
• Nikkaji Number: J3.064.553G
• Mol file: 14548-74-4.mol

Synonyms:14548-74-4;2,3,3,3-Tetrafluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)propan-1-ol;1H,1H-Perfluoro(2,5-dimethyl-3,6-dioxanonan-1-ol);1H,1H-2,5-DI(TRIFLUOROMETHYL)-3,6-DIOXAUNDECAFLUORONONANOL;2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propan-1-ol;Perfluoro(2-(2-propoxypropoxy)-1H,1H-propan-1-ol);1H,1H-Perfluoro(2,5-methyl-3,6-dioxanonan-1-ol);SCHEMBL3425694;DTXSID80371164;MFCD00339457;AKOS015911205;CF3CF2CF2OCF(CF3)CF2OCF(CF3)CH2OH;CS-0446678;FT-0607849;A808378;2-(1,1,2,2,3,3,3-Fluoropropoxy)propoxy)-1-propanol;1H,1H-Heptadecafluoro(2,5-dimethyl-3,6-dioxanonan-1-ol);1H,1H-2,5-Di(trifluoromethyl)-3,6-dioxa-undecafluorononanol;1H,1H-2,5-BIS(TRIFLUOROMETHYL)-3,6-DIOXA-PERFLUORONONANOL;2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(heptafluoropropoxy) propoxy]-1-propanol;2,5-bis-trifluoromethyl-2,4,4,5,7,7,8,8,9,9,9-undecafluoro-3,6-dioxanonanol;2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]-1-propanol;2,3,3,3-Tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propane-1-ol;2,3,3,3-tetrakis(fluoranyl)-2-[1,1,2,3,3,3-hexakis(fluoranyl)-2-[1,1,2,2,3,3,3-heptakis(fluoranyl)propoxy]propoxy]propan-1-ol

Chemical Property of 2,3,3,3-Tetrafluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)propan-1-ol

Chemical Property:

• Vapor Pressure: 0.00313mmHg at 25°C
• Refractive Index: 1.292
• Boiling Point: 251.9 °C at 760 mmHg
• PKA: 12.56±0.10(Predicted)
• Flash Point: 123 °C
• PSA: 38.69000
• Density: 1.719 g/cm³
• LogP: 4.85130
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 20
• Rotatable Bond Count: 7
• Exact Mass: 481.9810727
• Heavy Atom Count: 29
• Complexity: 576

Purity/Quality:

99% ^*data from raw suppliers

1H,1H-Perfluoro(2,5-dimethyl-3,6-dioxanonan-1-ol) 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(F)(F)F)(OC(C(C(F)(F)F)(OC(C(C(F)(F)F)(F)F)(F)F)F)(F)F)F)O
• Use Description: 1H,1H-2,5-Di(trifluoromethyl)-3,6-dioxaundecafluorononanol is a compound with specialized applications in different fields. In the field of chemistry and materials science, it serves as a valuable fluorinating agent, facilitating the introduction of trifluoromethyl groups into organic molecules. This compound plays a pivotal role in the development of fluorinated compounds with unique properties, such as enhanced chemical stability and altered reactivity, contributing to the creation of specialty chemicals and materials used in industries like pharmaceuticals and electronics. Additionally, in academic research, it can be employed as a reagent for the synthesis of complex organic molecules, aiding in the study of fluorination reactions and the development of new chemical methodologies. Its multifaceted utility underscores its significance in advancing synthetic chemistry, materials science, and academic research, where it plays a crucial role in compound synthesis, materials development, and chemical exploration.

Technology Process of 2,3,3,3-Tetrafluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)propan-1-ol

There total 4 articles about 2,3,3,3-Tetrafluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride (2641-34-1) → 2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(heptafluoropropoxy)propoxy]propan-1-ol (14548-74-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 2h; Inert atmosphere; Reflux;

Reference yield: 81.1%

methyl 2,4,4,5,7,7,8,8,9,9,9-undecafluoro-2,5-bis(trifluoromethyl)-3,6-dioxanonanoate (26131-32-8) → 2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(heptafluoropropoxy)propoxy]propan-1-ol (14548-74-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; diethyl ether; for 12h; Heating;

DOI:10.1016/S0022-1139(01)00562-0

Reference yield:

2,4,4,5,7,7,8,8,9,9,9-undecafluoro-2,5-bis(trifluoromethyl)-3,6-dioxanonyl trifluoromethanesulfonate (1173110-39-8) → 2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(heptafluoropropoxy)propoxy]propan-1-ol (14548-74-4)

Guidance literature:

With sodium hydride; phenol; In dimethyl sulfoxide; at 130 ℃; Inert atmosphere;

DOI:10.1135/cccc20081799

upstream raw materials:

methyl 2,4,4,5,7,7,8,8,9,9,9-undecafluoro-2,5-bis(trifluoromethyl)-3,6-dioxanonanoate

perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride

2,4,4,5,7,7,8,8,9,9,9-undecafluoro-2,5-bis(trifluoromethyl)-3,6-dioxanonyl trifluoromethanesulfonate

Refernces

• 1、 -. "Fluoroether acrylate monomer with 1,2,3-triazole group as linkage, and preparation method and application of fluoroether acrylate monomer". Paragraph 0037-0039. . Retrieved 2020/03/06.
• 2、 -. "PROCESS FOR PRODUCTION OF FLUORINATED SULFONYL FLUORIDES". Page/Page column 20. . Retrieved 2008/06/13.