2-Phenyl-4-hydroxypteridine

Base Information

• Chemical Name: 2-Phenyl-4-hydroxypteridine
• CAS No.: 23120-10-7
• Molecular Formula: C₁₂H₈N₄O
• Molecular Weight: 224.222
• Mol file: 23120-10-7.mol

Synonyms:2-phenylpteridin-4(3H)-one

Chemical Property of 2-Phenyl-4-hydroxypteridine

Chemical Property:

Purity/Quality:

95+% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Phenyl-4-hydroxypteridine

There total 14 articles about 2-Phenyl-4-hydroxypteridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

3-aminopyrazine-2-carboxamide (32587-10-3) + benzyl alcohol (100-51-6,185532-71-2) → 2-phenylpteridin-4(3H)-one (23120-10-7)

Guidance literature:

With iodine; sodium hydroxide; In water; at 20 ℃; for 6h; Electrochemical reaction; Green chemistry;

DOI:10.1039/d1ra02706a

Reference yield: 58.0%

2-amino-3-pyrazinonitrile (25911-65-3) + benzaldehyde (100-52-7) → 2-phenylpteridin-4(3H)-one (23120-10-7)

Guidance literature:

With water; iodine; sodium hydroxide; at 20 ℃; for 12h; Electrochemical reaction;

DOI:10.1039/d0ob02286a

Reference yield: 50.5%

Glyoxal (131543-46-9,107-22-2) + 6-chloro-2-phenylpyrimidine-4,5-diamine (424830-76-2) → 2-phenyl-4-hydroxypteridine (23120-10-7)

Guidance literature:

With acetic acid; In ethanol; water; for 1h; Heating;

DOI:10.1002/ardp.200600168

upstream raw materials:

Glyoxal

5,6-diamino-2-phenyl-3H-pyrimidin-4-one

2-Phenylpyrazino<2,3-d><3,1>oxazin-4-one

benzoyl chloride

Refernces

• 1、 Yang, Li,Hou, Huiqing,Li, Lan,Wang, Jin,Zhou, Sunying,Wu, Mei,Ke, Fang. "Electrochemically induced synthesis of quinazolinonesviacathode hydration ofo-aminobenzonitriles in aqueous solutions". supporting information. p. 998 - 1003. Retrieved 2021/02/16.
• 2、 Okawa, Tomohiro,Kawase, Masaru,Eguchi, Shoji. "A facile synthesis of 4(3H)-Pteridinone derivatives by utilizing N-{3-[(N-substituted)carbamoyl]-2- -pyrazyl}iminophosphoranes". . p. 1185 - 1194. Retrieved 2007/10/03.