C₂₆H₂₄N₃O₅P

Base Information

• Chemical Name: C₂₆H₂₄N₃O₅P
• CAS No.: 1417995-18-6
• Molecular Formula: C₂₆H₂₄N₃O₅P
• Molecular Weight: 489.467
• Mol file: 1417995-18-6.mol

Synonyms:C₂₆H₂₄N₃O₅P

Chemical Property of C₂₆H₂₄N₃O₅P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₄N₃O₅P

There total 2 articles about C₂₆H₂₄N₃O₅P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-Phenyl-1,2,4-triazolidine-3,5-dione (4233-33-4) + (E)-1-(dibenzyloxyphosphonyl)-1,3-butadiene (1240486-66-1) → C26H24N3O5P (1417995-18-6)

Guidance literature:

In 1,2-dichloro-ethane; for 1.5h; Reflux; Inert atmosphere;

DOI:10.1016/j.tet.2012.11.059

Reference yield:

tetrabenzyl methylenediphosphonate (133918-47-5) → C26H24N3O5P (1417995-18-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / toluene / 0.25 h / 20 °C / Inert atmosphere

1.2: 2 h / 20 °C / Inert atmosphere

2.1: 1,2-dichloro-ethane / 1.5 h / Reflux; Inert atmosphere

With sodium hydride; In 1,2-dichloro-ethane; toluene; 1.2: |Horner-Wadsworth-Emmons Olefination / 2.1: |Diels-Alder Cycloaddition;

DOI:10.1016/j.tet.2012.11.059

Reference yield: 100.0%

C26H24N3O5P (1417995-18-6) → tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-5-ylphosphonic acid (1417995-19-7)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃; under 760.051 Torr; Inert atmosphere;

DOI:10.1016/j.tet.2012.11.059

upstream raw materials:

4-Phenyl-1,2,4-triazolidine-3,5-dione

(E)-1-(dibenzyloxyphosphonyl)-1,3-butadiene

tetrabenzyl methylenediphosphonate

Downstream raw materials:

tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-5-ylphosphonic acid

Refernces