1-N-Boc-3-(R)-cyanopiperidine

Base Information

• Chemical Name: 1-N-Boc-3-(R)-cyanopiperidine
• CAS No.: 915226-44-7
• Molecular Formula: C₁₁H₁₈N₂O₂
• Molecular Weight: 210.276
• European Community (EC) Number: 676-075-4
• DSSTox Substance ID: DTXSID10427123
• Wikidata: Q72448991
• Mol file: 915226-44-7.mol

Synonyms:1-N-Boc-3-(R)-cyanopiperidine;915226-44-7;tert-butyl (3R)-3-cyanopiperidine-1-carboxylate;(r)-tert-butyl 3-cyanopiperidine-1-carboxylate;(R)-1-N-Boc-3-cyano-piperidine;(r)-1-boc-3-cyanopiperidine;(r)-1-n-boc-3-cyanopiperidine;(r)-3-cyano-piperidine-1-carboxylic acid tert-butyl ester;MFCD05864632;SCHEMBL4221580;DTXSID10427123;UEFZTXGFHKPSFS-VIFPVBQESA-N;1-n-boc-3-(r)-cyano-piperidine;AKOS007930621;DS-13466;CS-0028248;(r)-tert-butyl-3-cyanopiperidine-1-carboxylate;B66749;tert-butyl (R)-3-cyanopiperidine-1-carboxylate;Q-103084;1-Piperidinecarboxylic acid,3-cyano-,1,1-dimethylethyl ester,(3R)-;1-piperidinecarboxylic acid, 3-cyano-, 1,1-dimethylethyl ester, (3r)-;(R)-3-Cyanopiperidine-1-carboxylic acid tert-butyl ester;(R)-tert-butyl 3-cyanopiperidine-1-carboxylate

Chemical Property of 1-N-Boc-3-(R)-cyanopiperidine

Chemical Property:

• Vapor Pressure: 0.000232mmHg at 25°C
• Refractive Index: 1.487
• Boiling Point: 325.3 °C at 760 mmHg
• PKA: -3.42±0.40(Predicted)
• Flash Point: 150.5 °C
• PSA: 53.33000
• Density: 1.07 g/cm³
• LogP: 2.09498
• Storage Temp.: 2-8°C
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 210.136827821
• Heavy Atom Count: 15
• Complexity: 285

Purity/Quality:

99.3% ^*data from raw suppliers

(R)-tert-Butyl3-cyanopiperidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)N1CCCC(C1)C#N
• Isomeric SMILES: CC(C)(C)OC(=O)N1CCC[C@H](C1)C#N

Technology Process of 1-N-Boc-3-(R)-cyanopiperidine

There total 1 articles about 1-N-Boc-3-(R)-cyanopiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(R)-tert-butyl 3-carbamoylpiperidine-1-carboxylate (915226-43-6) → (R)-3-cyano-piperidine-1-carboxylic acid tert-butyl ester (915226-44-7)

Guidance literature:

With pyridine; trichlorophosphate; at 0 - 20 ℃;

upstream raw materials:

(R)-tert-butyl 3-carbamoylpiperidine-1-carboxylate

Refernces