Cis-3,5-Piperidinedicarboxylic acid

Base Information

• Chemical Name: Cis-3,5-Piperidinedicarboxylic acid
• CAS No.: 876367-84-9
• Molecular Formula: C₇H₁₁NO₄
• Molecular Weight: 173.169
• Mol file: 876367-84-9.mol

Synonyms:3,5-Piperidinedicarboxylicacid, cis- (7CI);3,5-piperidinedicarboxylic acid, (3R,5S)-;

Chemical Property of Cis-3,5-Piperidinedicarboxylic acid

Chemical Property:

• Refractive Index: 1.52
• Boiling Point: 362.3 °C at 760 mmHg
• Flash Point: 172.9 °C
• PSA: 86.63000
• Density: 1.363 g/cm³
• LogP: -0.28990

Purity/Quality:

99% ^*data from raw suppliers

cis-Piperidine-3,5-dicarboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cis-3,5-Piperidinedicarboxylic acid

There total 7 articles about Cis-3,5-Piperidinedicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

thiophene-2-carbaldehyde (98-03-3) + ammonium hydroxide (1336-21-6) + ethyl 4,4,4-trifluoroacetoacetate (372-31-6) → piperidine-3,5-Dicarboxylic Acid (121260-18-2,876367-84-9)

Guidance literature:

In ethanol;

Reference yield: 39.0%

furfural (98-01-1) + ethyl 4,4,4-trifluoroacetoacetate (372-31-6) → piperidine-3,5-Dicarboxylic Acid (121260-18-2,876367-84-9)

Guidance literature:

In ammonium hydroxide; ethanol;

Reference yield:

2H-pyran-3,5-dicarboxylic acid → piperidine-3,5-Dicarboxylic Acid (121260-18-2,876367-84-9)

Guidance literature:

With ammonium hydroxide; In ethanol;

upstream raw materials:

thiophene-2-carbaldehyde

ammonium hydroxide

ethyl 4,4,4-trifluoroacetoacetate

piperidine

Refernces