C₁₆H₁₃Cl₂NO₄

Base Information

• Chemical Name: C₁₆H₁₃Cl₂NO₄
• CAS No.: 1440061-93-7
• Molecular Formula: C₁₆H₁₃Cl₂NO₄
• Molecular Weight: 354.19
• Mol file: 1440061-93-7.mol

Synonyms:C₁₆H₁₃Cl₂NO₄

Chemical Property of C₁₆H₁₃Cl₂NO₄

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₁₆H₁₃Cl₂NO₄

There total 2 articles about C₁₆H₁₃Cl₂NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4'-Dichlorobiphenyl ether (6842-62-2) → C16H13Cl2NO4 (1440061-93-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

2: hydroxylamine hydrochloride / ethanol / 5 h / Reflux; Inert atmosphere

With aluminum (III) chloride; hydroxylamine hydrochloride; In ethanol; dichloromethane; 1: |Friedel-Crafts Acylation;

DOI:10.1039/c3nj00032j

Reference yield:

C16H12Cl2O4 (1440061-23-3) → C16H13Cl2NO4 (1440061-93-7)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; for 5h; Reflux; Inert atmosphere;

DOI:10.1039/c3nj00032j

Reference yield:

C16H13Cl2NO4 (1440061-93-7) → C14H13Cl2NO2 (1440062-60-1)

Guidance literature:

With sodium tetrahydroborate; iodine; In tetrahydrofuran; at 0 ℃; for 7.5h; Reflux; Inert atmosphere;

DOI:10.1039/c3nj00032j

upstream raw materials:

C₁₆H₁₂Cl₂O₄

3,4'-Dichlorobiphenyl ether

Downstream raw materials:

4-(2-chloro-4-(4-chlorophenoxy)phenyl)-2-(2,6-difluorophenyl)-1,3-oxazoline

C₂₁H₁₄Cl₃F₂NO₂

C₂₁H₁₅Cl₂F₂NO₃

C₁₄H₁₃Cl₂NO₂

Refernces