(4-Bromopyridin-2-yl)methanol

Base Information Edit

Chemical Name:(4-Bromopyridin-2-yl)methanol
CAS No.:131747-45-0
Molecular Formula:C6H6BrNO
Molecular Weight:188.024
Hs Code.:2933399090
European Community (EC) Number:812-912-3
DSSTox Substance ID:DTXSID80563704
Nikkaji Number:J2.768.596J
Wikidata:Q72511996
Mol file:131747-45-0.mol

Synonyms:(4-bromopyridin-2-yl)methanol;131747-45-0;4-Bromo-2-pyridinemethanol;(4-BROMO-2-PYRIDYL)METHANOL;2-PYRIDINEMETHANOL, 4-BROMO-;(4-Bromo-pyridin-2-yl)-methanol;(4-Bromo-2-pyridinyl)methanol;MFCD09800557;(4-bromanylpyridin-2-yl)methanol;4-Bromo-2-(hydroxymethyl)pyridine;IJF;4-BROMO-PYRIDINE-2-METHANOL;4-bromo-2-pyridylmethanol;SCHEMBL1879544;DTXSID80563704;MHVUUSQGWMQSMH-UHFFFAOYSA-N;AKOS005259296;CS-W018599;PB31388;AC-23727;AS-19522;SY021911;AM20050765;B5291;EN300-217663;W-205371

Suppliers and Price of (4-Bromopyridin-2-yl)methanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-2-pyridinemethanol
10g
$ 990.00

TCI Chemical
4-Bromo-2-pyridinemethanol >98.0%(GC)
1g
$ 83.00

SynQuest Laboratories
4-Bromopyridine-2-methanol
5 g
$ 500.00

SynQuest Laboratories
4-Bromopyridine-2-methanol
1 g
$ 150.00

Matrix Scientific
(4-Bromo-2-pyridyl)methanol >95%
5g
$ 159.00

Matrix Scientific
(4-Bromo-2-pyridyl)methanol >95%
500mg
$ 33.00

Matrix Scientific
(4-Bromo-2-pyridyl)methanol >95%
1g
$ 49.00

J&W Pharmlab
(4-Bromo-pyridin-2-yl)-methanol 96%
25g
$ 520.00

J&W Pharmlab
(4-Bromo-pyridin-2-yl)-methanol 96%
1g
$ 50.00

J&W Pharmlab
(4-Bromo-pyridin-2-yl)-methanol 96%
5g
$ 150.00

Total 71 raw suppliers

Chemical Property of (4-Bromopyridin-2-yl)methanol Edit

Chemical Property:

Vapor Pressure:0.00141mmHg at 25°C
Melting Point:52.0 to 56.0 °C
Refractive Index:1.598
Boiling Point:284.3 °C at 760 mmHg
PKA:13.09±0.10(Predicted)
Flash Point:125.7 °C
PSA：33.12000
Density:1.668 g/cm³
LogP:1.33640
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:186.96328
Heavy Atom Count:9
Complexity:89.1

Purity/Quality:

98% ^*data from raw suppliers

4-Bromo-2-pyridinemethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(C=C1Br)CO
Uses 4-Bromo-2-pyridinemethanol is used as a reagent to synthesize bisphosphonate derivatives, compounds that inhibit farnesyl pyrophosphate synthase (an important enzyme in isoprenoid biosynthesis).

Technology Process of (4-Bromopyridin-2-yl)methanol

There total 15 articles about (4-Bromopyridin-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 29681-42-3
methyl 4-bromopyridine-2-carboxylate

: 131747-45-0
4-bromo-2-(hydroxymethyl)pyridine

Guidance literature:: With sodium tetrahydroborate; ethanol; at 20 ℃; for 18h; Inert atmosphere;

Reference yield: 94.0%

: 192642-94-7
acetic acid 4-bromopyridin-2-ylmethyl ester

: 131747-45-0
4-bromo-2-(hydroxymethyl)pyridine

Guidance literature:: With hydrogenchloride; at 80 ℃; for 16h;
DOI:10.1016/S0040-4020(97)00491-2

Reference yield: 78.0%

: 100367-74-6
4-bromo-2-methylpyridine N-oxide

: 131747-45-0
4-bromo-2-(hydroxymethyl)pyridine

Guidance literature:: 4-bromo-2-methylpyridine N-oxide; With trifluoroacetic anhydride; In dichloromethane; at 0 - 22 ℃; for 44h; Inert atmosphere;

With potassium carbonate; In dichloromethane; water; tert-butyl alcohol; at 23 ℃; for 21h; Inert atmosphere;