(2,4-DICHLOROPHENYL)-METHANESULFONYL CHLORIDE

Base Information

• Chemical Name: (2,4-DICHLOROPHENYL)-METHANESULFONYL CHLORIDE
• CAS No.: 88691-50-3
• Molecular Formula: C7H5Cl3O2S
• Molecular Weight: 259.541
• Hs Code.: 2904909090
• Mol file: 88691-50-3.mol

Synonyms:a-Toluenesulfonyl chloride,2,4-dichloro- (6CI);(2,4-Dichlorophenyl)methanesulfonyl chloride;2,4-Dichlorobenzylsulfonyl chloride;

Chemical Property of (2,4-DICHLOROPHENYL)-METHANESULFONYL CHLORIDE

Chemical Property:

• Vapor Pressure: 8.81E-05mmHg at 25°C
• Melting Point: 83-85 °C
• Refractive Index: 1.589
• Boiling Point: 350.6 °C at 760 mmHg
• Flash Point: 165.8 °C
• PSA: 42.52000
• Density: 1.601 g/cm³
• LogP: 4.14280

Purity/Quality:

98%,99%, ^*data from raw suppliers

(2,4-Dichlorophenyl)methanesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2,4-DICHLOROPHENYL)-METHANESULFONYL CHLORIDE

There total 1 articles about (2,4-DICHLOROPHENYL)-METHANESULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-Dichlorobenzyl chloride (94-99-5) → (2,4-dichlorophenyl)methanesulfonyl chloride (88691-50-3)

Guidance literature:

With methanol; sodium thiosulfate; und Behandeln des Reaktionsprodukts mit Chlor und wss.Essigsaeure;

DOI:10.1021/jo01144a013

Reference yield: 98.0%

methyl 4-{2-[2-(2-aminoethyl)-1-benzhydryl-5-chloro-1H-indol-3-yl]ethoxy}benzoate amine (540522-69-8) + (2,4-dichlorophenyl)methanesulfonyl chloride (88691-50-3) → methyl 4-{2-[5-chloro-2-(2-{[(2,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy}benzoate (683813-13-0)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane;

DOI:10.1021/jm061131z

Reference yield: 81.6%

methyl 2-hydroxy-2-methylpropionate (2110-78-3) + (2,4-dichlorophenyl)methanesulfonyl chloride (88691-50-3) → methyl 2-{[(2,4-dichlorobenzyl)sulphonyl]oxy}-2-methylpropanoate (308851-22-1)

Guidance literature:

methyl 2-hydroxy-2-methylpropionate; With pyridine; at 0 ℃;

(2,4-dichlorophenyl)methanesulfonyl chloride; at 5 ℃; for 120h;

upstream raw materials:

2,4-Dichlorobenzyl chloride

Downstream raw materials:

[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-trimethyl-silane

C₁₄H₈Cl₄

trans-2,2',4,4'-tetrachlorostilbene

(2R,3R)-2,3-Bis-(2,4-dichloro-phenyl)-thiirane 1,1-dioxide

Refernces

• 1、 Bera, Milan,Agasti, Soumitra,Chowdhury, Rajdip,Mondal, Rahul,Pal, Debasis,Maiti, Debabrata. "Rhodium-Catalyzed meta-C?H Functionalization of Arenes". supporting information. p. 5272 - 5276. Retrieved 2017/04/27.
• 2、 Nakayama, Juzo,Tanuma, Mitsuru,Honda, Yoshiko,Hoshino, Masamatsu. "REACTION OF ARYLMETHANESULFONYL AND STYRYLMETHANESULFONYL CHLORIDES WITH TRIETHYLAMINE". . p. 4553 - 4556. Retrieved 2007/10/02.