Pyrazine-2-carbaldehyde

Base Information

• Chemical Name: Pyrazine-2-carbaldehyde
• CAS No.: 5780-66-5
• Molecular Formula: C5H4N2O
• Molecular Weight: 108.1
• Hs Code.: 29339900
• Mol file: 5780-66-5.mol

Synonyms:Pyrazinecarboxaldehyde(7CI,8CI,9CI);2-Formylpyrazine;2-Pyrazinecarboxaldehyde;

Chemical Property of Pyrazine-2-carbaldehyde

Chemical Property:

• Boiling Point: 192.079 °C at 760 mmHg
• PKA: -0.15±0.10(Predicted)
• Flash Point: 70.501 °C
• PSA: 42.85000
• Density: 1.235 g/cm³
• LogP: 0.28910
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99.9% ^*data from raw suppliers

Pyrazine-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrazine-2-carbaldehyde

There total 14 articles about Pyrazine-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl pyrazine-2-carboxylate (6164-79-0) → pyrazinecarboxaldehyde (5780-66-5)

Guidance literature:

methyl pyrazine-2-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 - 72 ℃; for 0.333333h;

With hydrogenchloride; water;

Reference yield: 96.8%

2-formalpyrazine → pyrazinecarboxaldehyde (5780-66-5)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; at 50 ℃; for 2h; Temperature;

Reference yield: 84.0%

→ methyl pyrazine-2-carboxylate (6164-79-0) + pyrazinecarboxaldehyde (5780-66-5)

Guidance literature:

upstream raw materials:

2,5-dimethyl-pyrazine

pyrazin-2-ylmethanol

methyl pyrazine-2-carboxylate

2-Methylpyrazine

Refernces

• 1、 Heath, Rachel S.,Birmingham, William R.,Thompson, Matthew P.,Taglieber, Andreas,Daviet, Laurent,Turner, Nicholas J.. "An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols". . p. 276 - 281. Retrieved 2019/01/04.
• 2、 Sarkari, Reema,Krishna, Vankudoth,Sudhakar, Medak,Rao, Tumula Venkateshwar,Padmasri, Aytam Hari,Srinivas, Darbha,Venugopal, Akula. "The effects of thermal treatment of ZnO–ZnCr2O4 catalyst on the particle size and product selectivity in dehydrocyclization of crude glycerol and ethylenediamine". . p. 602 - 609. Retrieved 2016/10/18.