Hept-1-ynyl-trimethyl-silane

Base Information

• Chemical Name: Hept-1-ynyl-trimethyl-silane
• CAS No.: 15719-56-9
• Molecular Formula: C10H20Si
• Molecular Weight: 168.354
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID80450004
• Nikkaji Number: J364.567C
• Mol file: 15719-56-9.mol

Synonyms:15719-56-9;Hept-1-ynyl-trimethyl-silane;1-HEPTYNYLTRIMETHYLSILANE;hept-1-ynyl(trimethyl)silane;Silane,1-heptyn-1-yltrimethyl-;hept-1-yn-1-yltrimethylsilane;Hept-1-ynyltrimethylsilane;1-(Trimethylsilyl)-1-heptyne;1-Heptynyltrimethylsilane, 95%;DTXSID80450004;ZEUUFOPEEQSBDA-UHFFFAOYSA-N;MFCD00053890;AKOS006343452;FT-0691069;J-802219

Chemical Property of Hept-1-ynyl-trimethyl-silane

Chemical Property:

• Vapor Pressure: 1.494mmHg at 25°C
• Refractive Index: 1.4344
• Boiling Point: 176.101 °C at 760 mmHg
• Flash Point: 47.697 °C
• PSA: 0.00000
• Density: 0.792 g/cm³
• LogP: 3.44750
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 168.133427172
• Heavy Atom Count: 11
• Complexity: 151

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-HEPTYNYLTRIMETHYLSILANE 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 10-36/37/38
• Safety Statements: 16-23-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC#C[Si](C)(C)C

Technology Process of Hept-1-ynyl-trimethyl-silane

There total 11 articles about Hept-1-ynyl-trimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

chloro-trimethyl-silane (75-77-4) + 1-Heptyne (628-71-7) → 1-heptynyltrimethylsilane (15719-56-9)

Guidance literature:

With diethylzinc; In hexane; acetonitrile; at 80 ℃; for 20h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.tetlet.2019.05.017

Reference yield: 61.0%

5-iodo-1-trimethylsilyl-1-pentyne (35761-91-2) + diethylzinc (557-20-0) → 1-heptynyltrimethylsilane (15719-56-9)

Guidance literature:

bis(acetylacetonate)nickel(II); In tetrahydrofuran; at -78 - -40 ℃; for 20h;

Reference yield:

1-Bromopentane (110-53-2) + trimethylsilylacetylene (1066-54-2) → 1-heptynyltrimethylsilane (15719-56-9)

Guidance literature:

With copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; triethylamine; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol503025n

upstream raw materials:

1-Heptene

chloro-trimethyl-silane

1-Heptyne

2-bromo-1-heptene

Downstream raw materials:

2-bromo-1-heptene

1-Heptyne

(E)-1-phenylthio-1-trimethylsilylheptene

(Dimethyl-{1-[1-trimethylsilanyl-meth-(E)-ylidene]-hexyl}-silanyl)-benzene

Refernces

• 1、 Skinner et al.. "". . p. 105,106, 108. Retrieved 1967.
• 2、 Nefedov,O.M. et al.. "-". . . Retrieved 1975.
• 3、 Huang, Pan,Xu, Dawen,Reich, Robert M.,Kaiser, Felix,Liu, Boping,Kühn, Fritz E.. "Et2Zn-mediated stoichiometric C(sp)-H silylation of 1-alkynes and chlorosilanes". supporting information. p. 1574 - 1577. Retrieved 2019/05/17.