1-[(4-Carboxyphenyl)methyl]-2-methyl-1,2-hydrazinedicarboxylic acid bis(phenylmethyl) ester

Base Information

• Chemical Name: 1-[(4-Carboxyphenyl)methyl]-2-methyl-1,2-hydrazinedicarboxylic acid bis(phenylmethyl) ester
• CAS No.: 18969-60-3
• Molecular Formula: C25H24 N2 O6
• Molecular Weight: 448.47
• Hs Code.: 2928000090
• Mol file: 18969-60-3.mol

Synonyms:1,2-Hydrazinedicarboxylicacid, 1-[(4-carboxyphenyl)methyl]-2-methyl-, bis(phenylmethyl) ester (9CI);Bicarbamic acid, (p-carboxybenzyl)methyl-, dibenzyl ester (7CI,8CI)

Chemical Property of 1-[(4-Carboxyphenyl)methyl]-2-methyl-1,2-hydrazinedicarboxylic acid bis(phenylmethyl) ester

Chemical Property:

• PSA: 108.66000
• Density: 1.304
• LogP: 4.61190

Purity/Quality:

99% ^*data from raw suppliers

(4-CARBOXYBENZYL)METHYLBICARBAMIC ACID DIBENZYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-[(4-Carboxyphenyl)methyl]-2-methyl-1,2-hydrazinedicarboxylic acid bis(phenylmethyl) ester

There total 1 articles about 1-[(4-Carboxyphenyl)methyl]-2-methyl-1,2-hydrazinedicarboxylic acid bis(phenylmethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Methyl 4-(bromomethyl)benzoate (2417-72-3) + 1-methyl-1,2-dicarbobenzoxy-hydrazine (6002-83-1) → 4-[(2-methyl-1,2-dicarbobenzoxy-hydrazino)-methyl]-benzoic acid (18969-60-3)

Guidance literature:

Multistep reaction; (i) NaH, DMF, (ii) aq. NaOH;

Reference yield:

4-[(2-methyl-1,2-dicarbobenzoxy-hydrazino)-methyl]-benzoic acid (18969-60-3) + isopropylamine (75-31-0) → 4-[(2-methyl-1,2-dicarbobenzoxyhydrazino)-methyl]-benzoic acid isopropylamide (58914-41-3)

Guidance literature:

In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane; benzene;

Reference yield:

4-[(2-methyl-1,2-dicarbobenzoxy-hydrazino)-methyl]-benzoic acid (18969-60-3) → Acetic acid 2-[4-(N'-methyl-hydrazinomethyl)-benzoylamino]-ethyl ester (47001-96-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium carbonate / diethyl ether

2: hydrogen bromide

With hydrogen bromide; sodium carbonate; In diethyl ether;

upstream raw materials:

Methyl 4-(bromomethyl)benzoate

1-methyl-1,2-dicarbobenzoxy-hydrazine

Downstream raw materials:

N-(1-Hydroxymethyl-propyl)-4-(N'-methyl-hydrazinomethyl)-benzamide

4-<(2-Methylhydrazino)-methyl>-benzoesaeure-isopentylamid

4-<(2-Methylhydrazino)-methyl>-benzoesaeure-sek.-butylamid

N-<4-<(2-Methyl-hydrazino)-methyl>-benzoyl>-glycin