Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate

Base Information Edit

Chemical Name:Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate
CAS No.:70406-92-7
Molecular Formula:C11H14Cl2N2O2
Molecular Weight:277.15
Hs Code.:2922499990
European Community (EC) Number:813-025-4
UNII:5395VIK2H2
DSSTox Substance ID:DTXSID60220681
Wikidata:Q27261079
Mol file:70406-92-7.mol

Synonyms:70406-92-7;Ethyl 2-((6-amino-2,3-dichlorobenzyl)amino)acetate;Ethyl N-(2,3-dichloro-6-aminobenzyl)glcycine;Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate;N-(6-amino-2,3-dichlorobenzyl)glycine ethyl ester;(6-AMINO-2,3-DICHLOROBENZYLAMINO)ACETIC ACID ETHYL ESTER;UNII-5395VIK2H2;ethyl N-(6-amino-2,3-dichlorobenzyl)glycine;Ethyl (2-amino-5,6-dichlorobenzyl)aminoacetate;5395VIK2H2;Glycine, N-((6-amino-2,3-dichlorophenyl)methyl)-, ethyl ester;(Anagrelide Impurity A);ethyl 2-[(6-amino-2,3-dichlorophenyl)methylamino]acetate;SCHEMBL278947;DTXSID60220681;GXKCDDOGWWCMAO-UHFFFAOYSA-N;BCPP000237;AMY33420;BCP22674;Ethyl 2-(6-Amino-2,3-dichlorobenzyl)glycine(Anagrelide Impurity A);AKOS022172483;AC-3495;BCP9000667;BS-17950;CS-0151572;FT-0668142;FT-0696704;ethyl 2-(6-amino-2,3-dichlorobenzyl-amino)acetate;N-(2-amino-5,6-dichlorobenzyl)glycine ethyl ester;Q27261079;Ethyl 2-(6-Amino-2,3-dichlorobenzyl)glycine Dihydrochloride;ETHYL 2-{[(6-AMINO-2,3-DICHLOROPHENYL)METHYL]AMINO}ACETATE

Suppliers and Price of Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-((6-amino-2,3-dichlorobenzyl)amino)acetate 95+%
1g
$ 491.00

Chemenu
Ethyl2-((6-amino-2,3-dichlorobenzyl)amino)acetate 95%
1g
$ 464.00

American Custom Chemicals Corporation
ETHYL-N-(2,3-DICHLORO-6-AMINOBENZYL)GLYCINE 98.00%
10G
$ 2165.63

Alichem
Ethyl2-((6-amino-2,3-dichlorobenzyl)amino)acetate
1g
$ 441.10

Total 38 raw suppliers

Chemical Property of Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.571
Boiling Point:402.412 °C at 760 mmHg
PKA:5.45±0.20(Predicted)
Flash Point:197.172 °C
PSA：64.35000
Density:1.318 g/cm³
LogP:3.20040
Storage Temp.:2-8°C(protect from light)
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:276.0432331
Heavy Atom Count:17
Complexity:254

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-((6-amino-2,3-dichlorobenzyl)amino)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CNCC1=C(C=CC(=C1Cl)Cl)N
Uses Anagrelide impurity A.

Technology Process of Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate

There total 6 articles about Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.6%

: 105-36-2
ethyl bromoacetate

: 2,3-dichloro-6-aminobenzylamine hydrochloride

: 70406-92-7
N-(6-amino-2,3-dichlorobenzyl)glycine ethyl ester

: (6,7-Dichloro-2-oxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl)-acetic acid ethyl ester

: [(6-Amino-2,3-dichloro-benzyl)-ethoxycarbonylmethyl-amino]-acetic acid ethyl ester

Guidance literature:: With triethylamine; In 1,4-dioxane; for 1h; Heating;
DOI:10.1002/prac.199633801129

Reference yield:

: 70380-50-6
N-(2,3-dichloro-6-nitrobenzyl)glycine ethyl ester hydrochloride

: 70406-92-7
N-(6-amino-2,3-dichlorobenzyl)glycine ethyl ester

Guidance literature:: N-(2,3-dichloro-6-nitrobenzyl)glycine ethyl ester hydrochloride; With hydrogenchloride; tin(ll) chloride; In water; at 15 - 45 ℃; for 3h;

With potassium carbonate; In water; at 0 - 5 ℃; pH=8.0 - 9.0;