pentafluoroprop-1-en-2-ol

Base Information

• Chemical Name: pentafluoroprop-1-en-2-ol
• CAS No.: 53841-56-8
• Molecular Formula: C₃HF₅O
• Molecular Weight: 148.032
• Mol file: 53841-56-8.mol

Synonyms:pentafluoroprop-1-en-2-ol

Chemical Property of pentafluoroprop-1-en-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of pentafluoroprop-1-en-2-ol

There total 2 articles about pentafluoroprop-1-en-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

Hexafluoroacetone (684-16-2) → perfluoropinacol (918-21-8) + 1,1,1,3,3,5,5,5-octafluoro-4-hydroxy-4-trifluoromethyl-pentan-2-one (52772-37-9) + pentafluoroprop-1-en-2-ol (53841-56-8) + 1,1,1,3,5,5,5-Heptafluoro-4-hydroxy-4-trifluoromethyl-pentan-2-one (115397-49-4)

Guidance literature:

With aluminium; mercury dichloride;

DOI:10.1007/BF00962047

Reference yield:

chloro-trimethyl-silane (75-77-4) + Hexafluoroacetone (684-16-2) → trimethylsilyl fluoride (420-56-4) + 1,1,1,3',3',3'-hexafluoro-propanol (920-66-1) + pentafluoroprop-1-en-2-ol (53841-56-8)

Guidance literature:

chloro-trimethyl-silane; Hexafluoroacetone; With magnesium; In N,N-dimethyl-formamide; at -20 - 0 ℃; for 1h;

With sulfuric acid; at -30 - 0 ℃; for 4h; Further stages. Title compound not separated from byproducts.;

DOI:10.1021/jo702568z

Reference yield:

pentafluoroprop-1-en-2-ol (53841-56-8) → chloropentafluoroacetone (79-53-8)

Guidance literature:

With tert-butylhypochlorite; sulfuric acid;

upstream raw materials:

Hexafluoroacetone

chloro-trimethyl-silane

Downstream raw materials:

Benzol-azo-pentafluoroacetonhydrat

p-Nitrobenzol-azo-pentafluoroacetonhydrat

chloropentafluoroacetone

Iodopentafluoroacetone

Refernces

• 1、 Zefirov, Yu. V.,Vol'pin, I. M.,Postovoi, S. A.,German, L. S.. "REDUCTIVE DEFLUORINATION OF HEXAFLUOROACETONE AND ITS ANIL". . p. 2225. Retrieved 2007/10/02.