rac 1-Oleoyl-3-palmitoylglycerol

Base Information

• Chemical Name: rac 1-Oleoyl-3-palmitoylglycerol
• CAS No.: 3343-30-4
• Molecular Formula: C₃₇H₇₀O₅
• Molecular Weight: 594.96
• Mol file: 3343-30-4.mol

Synonyms:2-hydroxy-3-(palmitoyloxy)propyl oleate

Chemical Property of rac 1-Oleoyl-3-palmitoylglycerol

Chemical Property:

• Melting Point: 39-41°C
• Boiling Point: 655.5±25.0 °C(Predicted)
• PKA: 12.63±0.20(Predicted)
• Density: 0.932±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Sparingly), DMSO, Ethyl Acetate (Slightly), Methanol (Slightly, Heat

Purity/Quality:

98%Min ^*data from raw suppliers

rac1-Oleoyl-3-palmitoylglycerol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of rac 1-Oleoyl-3-palmitoylglycerol

There total 3 articles about rac 1-Oleoyl-3-palmitoylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

cis-Octadecenoic acid (112-80-1,2027-47-6) + rac-1-monopalmitoylglycerol (305847-08-9) + dicyclohexyl-carbodiimide (538-75-0) → 2-hydroxy-3-(palmitoyloxy)propyl oleate (3343-30-4) + 1,3-Dicyclohexylurea (2387-23-7)

Guidance literature:

With dimethylaminopyridine; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

1-monooleoyl glycerol (111-03-5,2716-53-2,30836-40-9,34487-30-4,69483-90-5,99297-71-9,129784-87-8,33978-07-3,925-14-4) + vinyl palmitate (693-38-9) → 2-hydroxy-3-(palmitoyloxy)propyl oleate (3343-30-4)

Guidance literature:

With Lipozyme RM IM; In hexane; at 35 ℃; for 1h; Reagent/catalyst; Temperature; Time; Enzymatic reaction;

DOI:10.1016/j.procbio.2014.12.020

Reference yield:

2-Oleoylglycerol (3443-84-3,13822-11-2,116435-34-8) + n-hexadecanoyl chloride (112-67-4) → 2-hydroxy-3-(palmitoyloxy)propyl oleate (3343-30-4) + 1-palmitoyl-2-oleoyl-rac-glycerol (3123-73-7)

Guidance literature:

With pyridine; In chloroform; at 20 ℃; for 72h;

DOI:10.1023/A:1026425407150

upstream raw materials:

2-Oleoylglycerol

n-hexadecanoyl chloride

cis-Octadecenoic acid

rac-1-monopalmitoylglycerol

Downstream raw materials:

1,3-Dicyclohexylurea

2-linoleoyl-1-oleoyl-3-palmitoylglycerol

Refernces

• 1、 -. "Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof". Page/Page column 14. . Retrieved 2010/11/24.