sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate

Base Information

• Chemical Name: sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate
• CAS No.: 1013915-62-2
• Molecular Formula: C₈H₇BClF₃NO₃*Na
• Molecular Weight: 291.397
• Mol file: 1013915-62-2.mol

Synonyms:sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate

Chemical Property of sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate

There total 1 articles about sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

2-chloro-5-nitrobenzyl alcohol (80866-80-4) + pinacol (bromomethyl)boronate (166330-03-6) → sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate (1013915-62-2)

Guidance literature:

2-chloro-5-nitrobenzyl alcohol; pinacol (bromomethyl)boronate; With sodium hydride; In tetrahydrofuran; at 0 - 50 ℃; for 3.5h;

With sodium difluorohydrogenate; In tetrahydrofuran; at 0 ℃;

With water; In tetrahydrofuran; at 0 - 20 ℃; for 0.25h;

Reference yield: 58.0%

sodium 2-chloro-5-nitrobenzyloxymethyl trifluoroborate (1013915-62-2) → 5-nitro-1,3-dihydroisobenzofuran (52771-99-0)

Guidance literature:

With caesium carbonate; bis(tri-tert-butylphosphine)palladium⁽⁰⁾; In 1,4-dioxane; water; at 20 - 100 ℃;

upstream raw materials:

2-chloro-5-nitrobenzyl alcohol

pinacol (bromomethyl)boronate

Downstream raw materials:

5-nitro-1,3-dihydroisobenzofuran

Refernces