3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl)-

Base Information Edit

Chemical Name:3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl)-
CAS No.:147539-21-7
Molecular Formula:C12H20 N4
Molecular Weight:220.314
Hs Code.:
UNII:B8JI0GST1M
DSSTox Substance ID:DTXSID20933144
Nikkaji Number:J964.784H
Wikidata:Q82908950
Mol file:147539-21-7.mol

Synonyms:147539-21-7;3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl)-;B8JI0GST1M;2-piperazin-1-yl-N-propan-2-ylpyridin-3-amine;N-Isopropyl-2-(piperazin-1-yl)pyridin-3-amine;(3-N-Isopropylamino-2-piperazinyl)pyridine;N-Isopropyl-2(1-piperazinyl)-3-pyridinamine;U-88703;2-(Piperazin-1-yl)-N-(propan-2-yl)pyridin-3-amine;3-PYRIDYLAMINE, N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDE MONOHYDRATE;UNII-B8JI0GST1M;SCHEMBL2299768;DTXSID20933144;COALJHRGWIXLFP-UHFFFAOYSA-N;PNU-88703;AKOS015911817;2-piperazinyl-3-(isopropylamino)pyridine;1-[3-(N-isopropyl)amino-2-pyridinyl]piperazine;1-[3-(1-methylethylamino)-2-pyridinyl]piperazine;1 -[3-(1-Methylethylamino)-2-pyridinyl]piperazine;N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-3-PYRIDINAMINE;3-PYRIDYLAMINE,N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDEMONOHYDRATE

Suppliers and Price of 3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl)- Edit

Chemical Property:

Boiling Point:392.0±37.0 °C(Predicted)
PKA:9.17±0.30(Predicted)
PSA：49.42000
Density:1.080±0.06 g/cm3(Predicted)
LogP:3.31800
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:220.16879665
Heavy Atom Count:16
Complexity:201

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NC1=C(N=CC=C1)N2CCNCC2

Technology Process of 3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl)-

There total 8 articles about 3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 136818-14-9
1-[1,1-Dimethylethoxycarbonyl]-4-[3-(1-methylethylamino)-2-pyridinyl]piperazine

: 147539-21-7
[3-(1-methylethylamino)-2-pyridinyl]piperazine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 24.75h;

Reference yield:

: 153473-24-6
1-tert-butoxycarbonyl-4-(3-nitro-2-pyridyl)piperazine

: 147539-21-7
[3-(1-methylethylamino)-2-pyridinyl]piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / 10 percent Pd/C / methanol

2: NaCNBH₃ / methanol

3: CF₃COOH / CH₂Cl₂

With hydrogen; sodium cyanoborohydride; trifluoroacetic acid; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1248/cpb.49.1406

Reference yield:

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 147539-21-7
[3-(1-methylethylamino)-2-pyridinyl]piperazine

Guidance literature:: Multi-step reaction with 4 steps

1: CH₂Cl₂

2: H₂ / Pd

3: NaCNBH₃

4: TFA

With hydrogen; sodium cyanoborohydride; trifluoroacetic acid; palladium; In dichloromethane;
DOI:10.1002/jlcr.1283