2-Iodofuran

Base Information

• Chemical Name: 2-Iodofuran
• CAS No.: 54829-48-0
• Molecular Formula: C4H3IO
• Molecular Weight: 193.972
• Mol file: 54829-48-0.mol

Synonyms:2-Furyliodide;2-Iodofuran;

Chemical Property of 2-Iodofuran

Chemical Property:

• Vapor Pressure: 4.56mmHg at 25°C
• Melting Point: 242-244 °C
• Refractive Index: 1.582
• Boiling Point: 152.004 °C at 760 mmHg
• Flash Point: 45.731 °C
• PSA: 13.14000
• Density: 2.057 g/cm³
• LogP: 1.88420

Purity/Quality:

98%Min ^*data from raw suppliers

2-iodofuran 95%-98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Iodofuran

There total 1 articles about 2-Iodofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Furan-2-yl-m-tolyl-iodonium; iodide (85925-64-0) → 2-iodofuran (54829-48-0) + 3-Iodotoluene (625-95-6)

Guidance literature:

at 130 - 140 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/jo00163a022

Reference yield: 98.0%

2-iodofuran (54829-48-0) + dicyclohexylphosphine oxide (14717-29-4) → 2-furyl-di(c-hexyl)phosphine oxide (1415212-06-4)

Guidance literature:

With copper(l) iodide; potassium carbonate; triphenylphosphine; In toluene; at 110 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2012.10.064

Reference yield: 94.0%

2-iodofuran (54829-48-0) + 2'-O-(1-propyn-3-yl)-6-N-benzoyladenosine (210096-44-9) → 2'-O-(3-(furan-2-yl)-propyn-3-yl)-6-N-benzoyladenosine (1282033-18-4)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 55 ℃; Microwave irradiation;

DOI:10.1039/c0cc04667a

upstream raw materials:

Furan-2-yl-m-tolyl-iodonium; iodide

Downstream raw materials:

2-phenylfuran

2,2'-bifuran

2,2':5',2''-trifuran

2,2':5',2'':5'',2'''-quaterfuran

Refernces