ALLOFERON 1

Base Information

• Chemical Name: ALLOFERON 1
• CAS No.: 347884-61-1
• Molecular Formula: C52H76 N22 O16
• Molecular Weight: 1265.31
• Mol file: 347884-61-1.mol

Synonyms:Alloferon 1

Chemical Property of ALLOFERON 1

Chemical Property:

• PSA: 576.57000
• LogP: -3.70780

Purity/Quality:

98%Min ^*data from raw suppliers

Alloferon ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ALLOFERON 1

There total 1 articles about ALLOFERON 1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-gly-wang resin + N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + Fmoc-Val-OH (68858-20-8) + N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine (73724-45-5) + N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine (71989-20-3) + (9-fluorenylmethoxycarbonyl)-L-histidine (116611-64-4) → alloferon 1 (347884-61-1)

Guidance literature:

Fmoc-gly-wang resin; With piperidine; In N,N-dimethyl-formamide; wang resin

(9-fluorenylmethoxycarbonyl)-L-histidine; With 4-methyl-morpholine; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 2h; wang resin

N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Val-OH; N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine; N₂-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine; Further stages;

DOI:10.1016/j.bioorg.2016.03.002

upstream raw materials:

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-Val-OH

N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine

N₂-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine

Refernces