Benzyl Clavulanate

Base Information

• Chemical Name: Benzyl Clavulanate
• CAS No.: 57943-84-7
• Molecular Formula: C₁₅H₁₅NO₅
• Molecular Weight: 289.288
• Mol file: 57943-84-7.mol

Synonyms:Benzyl Clavulanate

Chemical Property of Benzyl Clavulanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzyl Clavulanate

There total 4 articles about Benzyl Clavulanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

potassium clavulanate (57943-81-4) → Benzyl Clavulanate (57943-84-7)

Guidance literature:

In N,N-dimethyl-formamide; for 1.5h; Ambient temperature;

Reference yield:

methyl clavulanate (57943-82-5) → Benzyl Clavulanate (57943-84-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / sodium hydroxide / H₂O / 1.17 h / 0 °C

2: 69 percent / dimethylformamide / 1.5 h / Ambient temperature

With sodium hydroxide; In water; N,N-dimethyl-formamide;

Reference yield:

clavulanic acid (58001-44-8) → Benzyl Clavulanate (57943-84-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / ethanol / Ambient temperature

2: 70 percent / sodium hydroxide / H₂O / 1.17 h / 0 °C

3: 69 percent / dimethylformamide / 1.5 h / Ambient temperature

With sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide;

upstream raw materials:

potassium clavulanate

methyl clavulanate

clavulanic acid

Downstream raw materials:

phenacyl isoclavulanate

p-bromobenzyl clavulanate

methyl clavulanate

clavulanic acid p-nitrobenzyl ester

Refernces