Buprofezin [iso]

Base Information

• Chemical Name: Buprofezin [iso]
• CAS No.: 953030-84-7
• Molecular Formula: C₁₆H₂₃N₃OS
• Molecular Weight: 305.444
• Mol file: 953030-84-7.mol

Synonyms:(Z)-2-[(1,1-dimethylethyl)imino]tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1,3,5-thiadiazin-4-one;(2Z)-3-Isopropyl-2-[(2-methyl-2-propanyl)imino]-5-phenyl-1,3,5-th iadiazinan-4-one;(2Z)-2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one;(Z)-2-tert-butylimino-3-isopropyl-5-phenyl-1,3,5-thiadiazinan-4-one;

Chemical Property of Buprofezin [iso]

Chemical Property:

• PSA: 61.21000
• LogP: 4.18510

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Buprofezin [iso]

There total 5 articles about Buprofezin [iso] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.3%

N-tert-butyl-N'-isopropylthiourea (52599-24-3) + N-Chloromethyl-N-phenylcarbamoyl chloride (52123-54-3) → buprofezin (69327-76-0,953030-84-7)

Guidance literature:

N-Chloromethyl-N-phenylcarbamoyl chloride; With dipotassium peroxodisulfate; 3,6-dimethyl-3,6-dihydroperoxy-4,5-dioxaoctane; at 40 - 45 ℃; Flow reactor; Large scale;

N-tert-butyl-N'-isopropylthiourea; With tetradecyltrimethylammonium chloride; calcium hydroxide; at 15 - 50 ℃; Reagent/catalyst; Temperature; Flow reactor; Large scale;

Reference yield:

N-methylaniline (100-61-8) → buprofezin (69327-76-0,953030-84-7)

Guidance literature:

Multi-step reaction with 3 steps

1: chlorine / chlorobenzene / 40 °C / Green chemistry

2: chlorobenzene / Green chemistry

3: sodium hydrogencarbonate / water; chlorobenzene / 5.5 h / 0 - 30 °C / Green chemistry

With chlorine; sodium hydrogencarbonate; In water; chlorobenzene;

Reference yield:

tert-butyl isothiocyanate (590-42-1) → buprofezin (69327-76-0,953030-84-7)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorobenzene / 1 h / 10 - 30 °C / Green chemistry

2: sodium hydrogencarbonate / water; chlorobenzene / 5.5 h / 0 - 30 °C / Green chemistry

With sodium hydrogencarbonate; In water; chlorobenzene;

upstream raw materials:

tert-butyl isothiocyanate

N-tert-butyl-N'-isopropylthiourea

N-Chloromethyl-N-phenylcarbamoyl chloride

N-methylaniline

Refernces

• 1、 -. "Synthesis method of buprofezin". Paragraph 0045; 0054-0081. . Retrieved 2019/08/03.
• 2、 -. "Buprofenzin process for the preparation of". Paragraph 0010; 0013-0015; 0018-0020; 0023-0025; 0028-0030. . Retrieved 2019/11/28.