N-CHLOROMETHYL-N-PHENYLCARBAMOYL CHLORIDE

Base Information

• Chemical Name: N-CHLOROMETHYL-N-PHENYLCARBAMOYL CHLORIDE
• CAS No.: 52123-54-3
• Molecular Formula: C8H7Cl2NO
• Molecular Weight: 204.056
• Hs Code.: 2903999090
• Mol file: 52123-54-3.mol

Synonyms:N-CHLOROMETHYL-N-PHENYLCARBAMOYL CHLORIDE;N-Chloromethyl-N-BenzenecarbamoylChloride;(CHLOROMETHYL)PHENYLCARBAMICCHLORIDE;N-chloromethyl-N-benzenecarbamoyl chloride N-chloromethyl-N-benzenecarbamoyl chloride

Chemical Property of N-CHLOROMETHYL-N-PHENYLCARBAMOYL CHLORIDE

Chemical Property:

• Melting Point: 45-46oC
• Boiling Point: 318.8±25.0 °C(Predicted)
• PKA: -0.48±0.50(Predicted)
• PSA: 20.31000
• Density: 1.385±0.06 g/cm3(Predicted)
• LogP: 3.04810

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-CHLOROMETHYL-N-PHENYLCARBAMOYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-CHLOROMETHYL-N-PHENYLCARBAMOYL CHLORIDE

There total 5 articles about N-CHLOROMETHYL-N-PHENYLCARBAMOYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

N-methyl-N-phenylformamide (93-61-8) → N-Chloromethyl-N-phenylcarbamoyl chloride (52123-54-3)

Guidance literature:

With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; Heating;

DOI:10.1016/S0022-1139(00)00287-6

Reference yield:

N-phenyl-N-methylcarbamoyl chloride (4285-42-1) → N-Chloromethyl-N-phenylcarbamoyl chloride (52123-54-3)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); chlorine; at 55 ℃;

Reference yield:

N-dichloromethyl-N-phenylcarbamoyl chloride → N-Chloromethyl-N-phenylcarbamoyl chloride (52123-54-3)

Guidance literature:

In chlorobenzene; Green chemistry;

upstream raw materials:

N-methyl-N-phenylformamide

N-methylaniline

N-phenyl-N-methylcarbamoyl chloride

Downstream raw materials:

2-tert-butylimino-3-isopropyl-5-phenyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazin-4-one

buprofezin

Refernces

• 1、 -. "Preparation method of buprofezin". Paragraph 0024; 0029; 0030. . Retrieved 2018/10/11.
• 2、 Liu, Suyou,Qian, Xuhong,Song, Gonghua,Chen, Jing,Chen, Weidong. "Fluorine containing heterocyclic compounds: Synthesis of 6-substituted-2-substituted-aryl-1,2,4-triazolo[5,1-b] 1,3,5-thiadiazin-7-one derivatives". . p. 111 - 115. Retrieved 2007/10/03.