4-AMINO-1-INDANONE

Base Information

• Chemical Name: 4-AMINO-1-INDANONE
• CAS No.: 51135-91-2
• Molecular Formula: C9H9NO
• Molecular Weight: 147.177
• Hs Code.: 2922399090
• Mol file: 51135-91-2.mol

Synonyms:1-Indanone,4-amino- (6CI);4-Amino-1-indanone;4-Amino-2,3-dihydro-1H-inden-1-one;1H-inden-1-one, 4-amino-2,3-dihydro-;4-Aminoindan-1-on;4-aminoindan-1-one;4-amino-2,3-dihydroinden-1-one;

Chemical Property of 4-AMINO-1-INDANONE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 122-123 °C
• Refractive Index: 1.65
• Boiling Point: 323.177 °C at 760 mmHg
• PKA: 3.20±0.20(Predicted)
• Flash Point: 149.252 °C
• PSA: 43.09000
• Density: 1.255 g/cm³
• LogP: 1.97890

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-1-indanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMINO-1-INDANONE

There total 11 articles about 4-AMINO-1-INDANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-nitro-2,3-dihydro-1H-inden-1-one (24623-25-4) → 4-amino-2,3-dihydro-1H-inden-1-one (51135-91-2)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; at 80 ℃; for 0.75h;

DOI:10.1016/j.tetlet.2020.152427

Reference yield: 90.0%

→ 4-amino-2,3-dihydro-1H-inden-1-one (51135-91-2)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; at 60 - 80 ℃;

Reference yield: 87.0%

4-nitro-2,3-dihydro-1H-inden-1-one (24623-25-4) + 6-nitroindan-1-one (24623-24-3) → 4-amino-2,3-dihydro-1H-inden-1-one (51135-91-2) + 6-aminoindan-1-one (69975-65-1)

Guidance literature:

With ammonium chloride; iron; In ethanol; at 90 ℃; for 1h;

upstream raw materials:

4-nitro-2,3-dihydro-1H-inden-1-one

2,2-dibromo-4-nitro-indan-1-one

inden-1-one

hydrogenchloride

Refernces

• 1、 -. "Synthesis of haloindenes". Page/Page column 4; 11. . Retrieved 2021/03/24.
• 2、 -. "COVALENT TARGETING OF E3 LIGASES". Paragraph 0591; 0602; 0700; 0724; 0816; 0843. . Retrieved 2020/05/19.