24623-24-3

Basic information

• Product Name: 6-NITROINDANONE
• Synonyms: 6-NITRO-INDAN-1-ONE;6-NITROINDANONE;6-NITRO-1-INDANONE;6-Nitro-1-indanone 98%;2,3-Dihydro-6-nitro-1H-inden-1-one;Einecs 246-366-7;2,3-dihydro-6-nitroinden-1-one;6-nitro-2,3-dihydroinden-1-one
• CAS NO: 24623-24-3
• Molecular Formula: C₉H₇NO₃
• Molecular Weight: 177.16
• EINECS: 246-366-7
• Mol File: 24623-24-3.mol
• Article Data: 27

Chemical Properties

• Melting Point: 71-73 °C
• Boiling Point: 331.964 °C at 760 mmHg
• Flash Point: 169.766 °C
• Appearance: /
• Density: 1.396 g/cm³
• Vapor Pressure: 0.00015mmHg at 25°C
• Refractive Index: 1.629
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 6-NITROINDANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-NITROINDANONE(24623-24-3)
• EPA Substance Registry System: 6-NITROINDANONE(24623-24-3)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-40
• Safety Statements: 26-36/37/39-45-36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 24623-24-3(Hazardous Substances Data)

Usage

General Description

6-Nitroindanone is a chemical compound with the molecular formula C9H7NO3. It is a pale yellow solid with a molecular weight of 173.16 g/mol. 6-Nitroindanone is used in the synthesis of various organic compounds and is also employed as an intermediate in the preparation of pharmaceuticals, agrochemicals, and other specialty chemicals. It is known for its strong nitroaromatic characteristics and is commonly used in organic reactions such as nucleophilic additions and condensations. 6-Nitroindanone is considered a useful building block in the production of various complex organic compounds due to its versatile reactivity and functional group compatibility.

InChI:InChI=1/C9H7NO3/c11-9-4-2-6-1-3-7(10(12)13)5-8(6)9/h1,3,5H,2,4H2

Upstream product

• 83-33-0 inden-1-one 
• 16642-79-8 3-(4-nitrophenyl)propionic acid 
• 496-11-7 INDANE 

Downstream Products

• 62658-54-2 6-nitro-indan-1-ylamine 
• 14548-40-4 6-iodo-2,3-dihydro-1H-inden-1-one 
• 22246-24-8 5-nitro-2,3-dihydroinden-1-one 
• 7436-07-9 5-nitroindane 
• 24425-40-9 indan-5-amine 

Relevant articles and documents

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An efficient and convenient protocol for the synthesis of 1,1-difluoro-6-nitro-2,3-dihydro-1 H -indene derivatives

A convenient and efficient synthesis of gem-difluorinated compounds is reported. The synthetic route toward various 2-substituted and 3-substituted 1,1-difluoro-6-nitro-2,3-dihydro-1H-indene derivatives is described starting from commercially available indanone. The key gem-difluorination step is accomplished in good yield by treatment of in situ generated bromine fluoride (BrF) with a dithioketal. A plausible mechanism discussing the competition between substitution and elimination is provided to rationalize the outcome of the reactions of the 3-brominated compounds with different amines. Georg Thieme Verlag Stuttgart New York.

METHODS FOR MAKING QUINOLINYLDIAMINES

The present disclosure provides methods for making quinolinyldiamine products from quinolinyl starting materials. In addition, the quinolinyldiamines can be used as ligands or ligand precursors for catalysts, e.g. for use in olefin polymerization.

BRD4-JAK2 INHIBITORS

Disclosed herein are compounds that are inhibitors of BDR4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BDR4 are also disclosed. In certain aspects, disclosed are compounds of Formula I, II, and II.