3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin

Base Information

• Chemical Name: 3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin
• CAS No.: 115029-70-4
• Molecular Formula: C₁₉H₁₆S₂
• Molecular Weight: 308.468
• Mol file: 115029-70-4.mol

Synonyms:3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin

Chemical Property of 3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin

There total 2 articles about 3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzaldehyde (100-52-7) + 1,8-bis(mercaptomethyl)naphthalene (60948-99-4) → 3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin (115029-70-4)

Guidance literature:

boron trifluoride diethyl etherate; In chloroform; 0 deg C, 2 h and 18 h, room t.;

DOI:10.1246/bcsj.62.3024

Reference yield:

naphthalene-1,8-diyldimethanol (2026-08-6) → 3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin (115029-70-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 94 percent / PBr₂ / dioxane / 25 h / Ambient temperature

2: aq. ethanol / 4 h / Heating

3: KOH / H₂O / 1 h / Heating

4: 97 percent / BF₃*Et₂O / CHCl₃ / 0 deg C, 2 h and 18 h, room t.

With potassium hydroxide; boron trifluoride diethyl etherate; In 1,4-dioxane; ethanol; chloroform; water;

DOI:10.1246/bcsj.62.3024

Reference yield: 38.0%

3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin (115029-70-4) → 3-phenyl-1H,5H-naphtho[1,8-ef][1,3]dithiocine 2-oxide

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃;

DOI:10.1007/s11178-005-0297-5

upstream raw materials:

benzaldehyde

1,8-bis(mercaptomethyl)naphthalene

naphthalene-1,8-diyldimethanol

Refernces

• 1、 Klimovitskii, E. N.,Sergeeva, G. N.,Il'yasov, K. A.,Latipov, V. V.,Klochkov, V. V.,et al.. "SYNTHESIS AND CONFORMATIONS OF EIGHT-MEMBERED DITHIOACETALS CONTAINING A NAPHTHALENE FRAGMENT". . p. 1974 - 1980. Retrieved 2007/10/02.