2-amino-4-bromo-5-methylphenol

Base Information

• Chemical Name: 2-amino-4-bromo-5-methylphenol
• CAS No.: 848358-81-6
• Molecular Formula: C7H8BrNO
• Molecular Weight: 202.051
• Hs Code.: 2922299090
• Mol file: 848358-81-6.mol

Synonyms:m-Cresol,6-amino-4-bromo- (1CI);2-Amino-4-bromo-5-methylphenol;

Chemical Property of 2-amino-4-bromo-5-methylphenol

Chemical Property:

• Vapor Pressure: 0.00136mmHg at 25°C
• Refractive Index: 1.653
• Boiling Point: 288.3 °C at 760 mmHg
• PKA: 9.31±0.23(Predicted)
• Flash Point: 128.1 °C
• PSA: 46.25000
• Density: 1.647 g/cm³
• LogP: 2.62650
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98% ^*data from raw suppliers

2-Amino-4-bromo-5-methylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-amino-4-bromo-5-methylphenol

There total 1 articles about 2-amino-4-bromo-5-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-bromo-5-methyl-2-nitrophenol (182500-28-3) → 2-amino-4-bromo-5-methylphenol (848358-81-6)

Guidance literature:

With hydrogenchloride; tin(II) chloride dihdyrate; In methanol; at 75 ℃; for 2h;

Reference yield:

2-amino-4-bromo-5-methylphenol (848358-81-6) → acetic acid-(5-bromo-2-hydroxy-4-methyl-anilide) (857616-88-7)

Guidance literature:

Multi-step reaction with 2 steps

2: pyridine

With pyridine;

DOI:10.1021/ja01221a506

Reference yield:

2-amino-4-bromo-5-methylphenol (848358-81-6) → 5-acetoxy-4-benzoylamino-2-bromo-toluene

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: sodium acetate

With diethyl ether; sodium acetate;

upstream raw materials:

4-bromo-5-methyl-2-nitrophenol

Downstream raw materials:

acetic acid-(5-bromo-2-hydroxy-4-methyl-anilide)

Refernces