2,2'-Bipyridine-3,3'-diol

Base Information

• Chemical Name: 2,2'-Bipyridine-3,3'-diol
• CAS No.: 36145-03-6
• Molecular Formula: C10H8N2O2
• Molecular Weight: 188.186
• Hs Code.: 2933399090
• Mol file: 36145-03-6.mol

Synonyms:2,2'-Bipyridyl-3,3,-diol;2,2'-Bis(3-pyridinol);2,2'-Bypyridine-3,3'-diol;2,2'-Dipyridine-3,3'-diol;3,3'-Dihydroxy-2,2'-bipyridine;[2,2'-Bipyridyl]-3,3'-diol;

Chemical Property of 2,2'-Bipyridine-3,3'-diol

Chemical Property:

• Melting Point: 194-196 °C(lit.)
• Boiling Point: 528.194 °C at 760 mmHg
• PKA: 8.26±0.10(Predicted)
• Flash Point: 273.242 °C
• PSA: 66.24000
• Density: 1.363 g/cm³
• LogP: 1.55480

Purity/Quality:

99% ^*data from raw suppliers

2,2''-Bipyridine-3,3''-diol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-Bipyridine-3,3'-diol

There total 22 articles about 2,2'-Bipyridine-3,3'-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

3,3'-dimethoxy-2,2'-bipyridine (93560-59-9) → [2,2'-bipyridine]-3,3'-diol (36145-03-6)

Guidance literature:

With pyridine hydrochloride; for 4h; Heating;

Reference yield: 62.0%

(2-Furyl)(3-methoxy-2-pyridyl)keton (93560-50-0) → 3'-Methoxy-2,2'-bipyridin-3-ol (87385-13-5) + [2,2'-bipyridine]-3,3'-diol (36145-03-6)

Guidance literature:

With ammonium acetate; at 150 ℃; for 2h; Yields of byproduct given;

Reference yield: 55.0%

2-bromo-pyridin-3-ol (6602-32-0) → [2,2'-bipyridine]-3,3'-diol (36145-03-6)

Guidance literature:

With nickel; triphenylphosphine; zinc; In N,N-dimethyl-formamide; at 50 ℃; for 3h;

DOI:10.1055/s-1990-26852

upstream raw materials:

2-bromo-pyridin-3-ol

furil

3,3'-dimethoxy-2,2'-bipyridine

2-Brom-3-(tetrahydro-2-pyranyloxy)pyridin

Downstream raw materials:

[(η5-C5Me4C5H5)Ir(bipy(OH)2)Cl]PF6

[(η6-biphenyl)Ru(2,2'-bipyridine-3,3'-diol(1-))Cl]

Refernces

• 1、 Naumann, Christoph,Langhals, Heinz. "A Simple Synthesis of Dihydroxybipyridyls". . p. 279 - 281. Retrieved 1990.
• 2、 Mongin, Florence,Trécourt, Fran?ois,Mongin, Olivier,Quéguiner, Guy. "New syntheses of orelline and analogues via metalation and cross-coupling reactions". . p. 309 - 314. Retrieved 2007/10/03.