Methyl4-amino-2-methylbenzoate

Base Information

• Chemical Name: Methyl4-amino-2-methylbenzoate
• CAS No.: 6933-47-7
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Hs Code.: 2922499990
• Mol file: 6933-47-7.mol

Synonyms:o-Toluicacid, 4-amino-, methyl ester (6CI,7CI,8CI);4-Amino-2-methylbenzoic acid methylester;Methyl 4-amino-2-methylbenzoate;

Chemical Property of Methyl4-amino-2-methylbenzoate

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.559
• Boiling Point: 302.417 °C at 760 mmHg
• PKA: 2.59±0.10(Predicted)
• Flash Point: 157.5 °C
• PSA: 52.32000
• Density: 1.132 g/cm³
• LogP: 1.94500
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99% ^*data from raw suppliers

Methyl4-Amino-2-methylbenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl4-amino-2-methylbenzoate

There total 4 articles about Methyl4-amino-2-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 2-methyl-4-nitrobenzoate (62621-09-4) → methyl 4-amino-2-methylbenzoate (6933-47-7)

Guidance literature:

With ammonium formate; palladium 10% on activated carbon; In ethanol; at 40 ℃; for 2h;

Reference yield: 100.0%

methanol (67-56-1) + 4-acetylamino-2-methylbenzoic acid (103204-69-9) → methyl 4-amino-2-methylbenzoate (6933-47-7)

Guidance literature:

methanol; 4-acetylamino-2-methylbenzoic acid; With sulfuric acid; for 3h; Heating / reflux;

With sodium hydroxide; In water; at 0 ℃; Alkaline aqueous solution;

Reference yield: 85.0%

methanol (67-56-1) + 4-amino-2-methylbenzoic acid (2486-75-1) → methyl 4-amino-2-methylbenzoate (6933-47-7)

Guidance literature:

With hydrogenchloride; In water; Reflux;

upstream raw materials:

methyl 2-methyl-4-nitrobenzoate

methanol

4-acetylamino-2-methylbenzoic acid

methyl 4-acetamido-2-methylbenzoate

Downstream raw materials:

methyl 2,5-dimethyl-4-propionylaminobenzoate

methyl 2,3-dimethyl-4-propionylaminobenzoate

2,3-dimethyl-4-propionylamino-benzoic acid

2,5-dimethyl-4-propionylamino-benzoic acid

Refernces

• 1、 -. "THIAZOLIDINONE COMPOUNDS AND USE THEREOF". Paragraph 0175-0176. . Retrieved 2017/09/21.
• 2、 -. "Insecticidal 4-phenyl-1H-pyrazoles". Page/Page column 28. . Retrieved 2011/08/08.