62621-09-4

Basic information

• Product Name: Methyl 2-Methyl-4-nitrobenzoate
• Synonyms: Methyl 2-Methyl-4-nitrobenzoate;Benzoic acid, 2-Methyl-4-nitro-, Methyl ester;Methyl 4-Nitro-2-Methylbenzoate;2-Methyl-4-nitrobenzoic acid methyl ester;_x005f\rMethyl 2-Methyl-4-nitrobenzoate
• CAS NO: 62621-09-4
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195.18
• Product Categories: Esters;Phenyls & Phenyl-Het
• Mol File: 62621-09-4.mol
• Article Data: 25

Chemical Properties

• Melting Point: 74.0 to 78.0 °C
• Boiling Point: 315.445 °C at 760 mmHg
• Flash Point: 148.51 °C
• Appearance: /
• Density: 1.256 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: Methyl 2-Methyl-4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-Methyl-4-nitrobenzoate(62621-09-4)
• EPA Substance Registry System: Methyl 2-Methyl-4-nitrobenzoate(62621-09-4)

Safety Data

• Hazardous Substances Data: 62621-09-4(Hazardous Substances Data)

Usage

Uses

methyl 2-methyl-4-nitrobenzoate is a useful research chemical.

InChI:InChI=1/C9H9NO4/c1-6-5-7(10(12)13)3-4-8(6)9(11)14-2/h3-5H,1-2H3

Upstream product

• 67-56-1 methanol 
• 30459-70-2 2-methyl-4-nitrobenzoyl chloride 
• 1975-51-5 2-methyl-4-nitrobenzoic acid 
• 201230-82-2 carbon monoxide 
• 5326-38-5 2-iodo-5-nitrotoluene 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 89001-53-6 2-cyano-5-nitrotoluene 
• 99584-16-4 2-methyl-4-nitro-benzoic acid amide 
• 74-88-4 methyl iodide 
• 124-41-4 sodium methylate 

Downstream Products

• 1221486-69-6 2-(3-Acetylaminophenoxymethyl)-4-nitrobenzoic acid methyl ester 
• 1221486-70-9 2-(3-Acetylaminophenoxymethyl)-4-nitrobenzoic acid 
• 928032-23-9 6-nitroisoquinolin-1(2H)-one 
• 6933-47-7 methyl 4-amino-2-methylbenzoate 

Relevant articles and documents

Influence of Linker Attachment Points on the Stability and Neosubstrate Degradation of Cereblon Ligands

Proteolysis targeting chimeras (PROTACs) hijacking the cereblon (CRBN) E3 ubiquitin ligase have emerged as a novel paradigm in drug development. Herein we found that linker attachment points of CRBN ligands highly affect their aqueous stability and neosubstrate degradation features. This work provides a blueprint for the assembly of future heterodimeric CRBN-based degraders with tailored properties.

MONOCARBOXYLATE TRANSPORT MODULATORS AND USES THEREOF

The invention generally relates to the field of monocarboxylate transport modulators, e.g., monocarboxylate transport inhibitors, and more particularly to new substituted-quinolone compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in treating, modulating, forestalling and/or reducing physiological conditions associated with monocarboxylate transport activity such as in treating cancer and other neoplastic disorders, inflammatory diseases, disorders of abnormal tissue growth and fibrosis including cardiomyopathy, obesity, diabetes, cardiovascular diseases, tissue and organ transplant rejection, and malaria.

Method for synthesizing 2-azidomethyl-4-nitrobenzoyl chloride

The invention provides a synthetic route for a novel protective group, namely 2-azidomethyl-4-nitrobenzoyl chloride. 2-methyl-4-nitrobenzoic acid is used as a raw material, and the 2-azidomethyl-4-nitrobenzoyl chloride is synthesized through the five step