1-BROMO-2-(PHENOXYMETHYL)BENZENE 97+%

Base Information

• Chemical Name: 1-BROMO-2-(PHENOXYMETHYL)BENZENE 97+%
• CAS No.: 94191-73-8
• Molecular Formula: C13H11 Br O
• Molecular Weight: 263.134
• Hs Code.: 2909309090
• Mol file: 94191-73-8.mol

Synonyms:1-Bromo-2-(phenoxymethyl)benzene;2-Bromobenzyl phenyl ether

Chemical Property of 1-BROMO-2-(PHENOXYMETHYL)BENZENE 97+%

Chemical Property:

• Vapor Pressure: 0.000175mmHg at 25°C
• Melting Point: 41 °C
• Boiling Point: 339.9°C at 760 mmHg
• Flash Point: 139.8°C
• PSA: 9.23000
• Density: 1.382g/cm³
• LogP: 4.02810
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

1-Bromo-2-(phenoxymethyl)benzene 97.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BROMO-2-(PHENOXYMETHYL)BENZENE 97+%

There total 10 articles about 1-BROMO-2-(PHENOXYMETHYL)BENZENE 97+% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

phenol (108-95-2,27073-41-2) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → 1-bromo-2-(phenoxymethyl)benzene (94191-73-8)

Guidance literature:

With potassium carbonate; In acetone; for 14h; Inert atmosphere; Schlenk technique; Reflux;

DOI:10.1021/jacv6b10018

Reference yield: 62.0%

2-bromobenzylchloride (578-51-8) + phenol (108-95-2,27073-41-2) → 1-bromo-2-(phenoxymethyl)benzene (94191-73-8)

Guidance literature:

phenol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h; Inert atmosphere;

2-bromobenzylchloride; In N,N-dimethyl-formamide; for 3.16667h;

DOI:10.1016/j.bmc.2011.10.087

Reference yield: 36.0%

o-bromobenzyl alcohol (18982-54-2) + 2-(trimethylsilyl)phenyl trifluoromethanesulfonate (88284-48-4) → 1-bromo-2-(phenoxymethyl)benzene (94191-73-8)

Guidance literature:

With cesium fluoride; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1021/jo0602221

upstream raw materials:

sodium phenoxide

2-bromobenzylchloride

phenol

1-Bromo-2-bromomethyl-benzene

Downstream raw materials:

2-(phenoxymethyl)benzoic acid

C₃₃H₄₃NO₄S

(R)-2-(2-(phenoxymethyl)benzamido)-3-(((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)thio)propanoic acid

2-phenylbenzofuran

Refernces

• 1、 Li, Ya-Wei,Zheng, Hong-Xing,Yang, Bo,Shan, Xiang-Huan,Qu, Jian-Ping,Kang, Yan-Biao. "tBuOK-Promoted Cyclization of Imines with Aryl Halides". supporting information. p. 4553 - 4556. Retrieved 2020/06/08.
• 2、 Tanji, Yutaka,Mitsutake, Naoya,Fujihara, Tetsuaki,Tsuji, Yasushi. "Steric Effect of Carboxylate Ligands on Pd-Catalyzed Intramolecular C(sp2)–H and C(sp3)–H Arylation Reactions". supporting information. p. 10314 - 10317. Retrieved 2018/08/06.