2-Pyridinemethanol,3,6-dimethyl-

Base Information

• Chemical Name: 2-Pyridinemethanol,3,6-dimethyl-
• CAS No.: 848774-90-3
• Molecular Formula: C8H11NO
• Molecular Weight: 137.181
• Hs Code.: 2933399090
• Mol file: 848774-90-3.mol

Synonyms:(3,6-Dimethylpyridin-2-yl)methanol; 2-pyridinemethanol, 3,6-dimethyl-; LogP

Chemical Property of 2-Pyridinemethanol,3,6-dimethyl-

Chemical Property:

• Vapor Pressure: 0.0219mmHg at 25°C
• Refractive Index: 1.539
• Boiling Point: 239.4 °C at 760 mmHg
• Flash Point: 98.6 °C
• PSA: 33.12000
• Density: 1.063 g/cm³
• LogP: 1.19070
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

(3,6-Dimethylpyridin-2-yl)methanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Pyridinemethanol,3,6-dimethyl-

There total 3 articles about 2-Pyridinemethanol,3,6-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

3,6-dimethylpyridine-2-carbonitrile (68164-77-2) → (3,6-dimethylpyridin-2-yl)methanol (848774-90-3)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; for 2h; under 1551.44 Torr;

DOI:10.1021/jm040883v

Reference yield:

2,5-dimethylpyridine N-oxide (4986-05-4) → (3,6-dimethylpyridin-2-yl)methanol (848774-90-3)

Guidance literature:

Multi-step reaction with 3 steps

1: CH₂Cl₂ / 0.42 h / 20 °C

2: 9.72 g / Et₂NCOCl / CH₂Cl₂ / 96 h / 20 °C

3: 57 percent / H₂; aq. HCl / Pd/C / 2 h / 1551.44 Torr

With hydrogenchloride; hydrogen; N,N-diethylcarbamyl chloride; palladium on activated charcoal; In dichloromethane;

DOI:10.1021/jm040883v

Reference yield:

2-cyano-3,6-dimethylpyridine 1-oxide (892665-90-6) → (3,6-dimethylpyridin-2-yl)methanol (848774-90-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 9.72 g / Et₂NCOCl / CH₂Cl₂ / 96 h / 20 °C

2: 57 percent / H₂; aq. HCl / Pd/C / 2 h / 1551.44 Torr

With hydrogenchloride; hydrogen; N,N-diethylcarbamyl chloride; palladium on activated charcoal; In dichloromethane;

DOI:10.1021/jm040883v

upstream raw materials:

3,6-dimethylpyridine-2-carbonitrile

2,5-dimethylpyridine N-oxide

2-cyano-3,6-dimethylpyridine 1-oxide

Refernces