2,3-DIMETHYL-5-ISOPROPYLPYRAZINE

Base Information

• Chemical Name: 2,3-DIMETHYL-5-ISOPROPYLPYRAZINE
• CAS No.: 40790-21-4
• Molecular Formula: C₉H₁₄N₂
• Molecular Weight: 150.224
• Hs Code.: 2933990090
• Mol file: 40790-21-4.mol

Synonyms:2,3-Dimethyl-5-isopropylpyrazine;5-Isopropyl-2,3-dimethylpyrazine;

Chemical Property of 2,3-DIMETHYL-5-ISOPROPYLPYRAZINE

Chemical Property:

• Vapor Pressure: 0.334mmHg at 25°C
• Refractive Index: 1.495
• Boiling Point: 206.9 °C at 760 mmHg
• Flash Point: 77 °C
• PSA: 25.78000
• Density: 0.947 g/cm³
• LogP: 2.21680
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

5-Isopropyl-2,3-dimethylpyrazine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-DIMETHYL-5-ISOPROPYLPYRAZINE

There total 7 articles about 2,3-DIMETHYL-5-ISOPROPYLPYRAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,3-dimethyl-5-trifluoromethanesulfonyloxypyrazine (1147535-04-3) + isopropyl zinc bromide (77047-87-1) → 5-isopropyl-2,3-dimethylpyrazine (40790-21-4)

Guidance literature:

With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1055/s-0031-1290972

Reference yield: 63.0%

2,3-dimethyl-5-trifluoromethanesulfonyloxypyrazine (1147535-04-3) + diisopropyl zinc (625-81-0) → 5-isopropyl-2,3-dimethylpyrazine (40790-21-4)

Guidance literature:

With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1055/s-0031-1290972

Reference yield: 35.0%

2,3-dimethyl-5-trifluoromethanesulfonyloxypyrazine (1147535-04-3) + isopropylmagnesium chloride (1068-55-9) → 5-isopropyl-2,3-dimethylpyrazine (40790-21-4)

Guidance literature:

With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1055/s-0031-1290972

upstream raw materials:

2,3-dimethyl-5-trifluoromethanesulfonyloxypyrazine

isopropylmagnesium chloride

diisopropyl zinc

isopropyl zinc bromide

Refernces