Isopropylamine hydrochloride

Base Information

• Chemical Name: Isopropylamine hydrochloride
• CAS No.: 15572-56-2
• Molecular Formula: C3H9 N . Cl H
• Molecular Weight: 95.5721
• Hs Code.: 2921199090
• European Community (EC) Number: 239-629-2
• DSSTox Substance ID: DTXSID40884841
• Mol file: 15572-56-2.mol

Synonyms:Isopropylamine hydrochloride;15572-56-2;propan-2-amine hydrochloride;2-Propanamine, hydrochloride;2-Aminopropane Hydrochloride;Isopropyl amine hydrochloride;2-Propanamine, hydrochloride (1:1);iso-propylamine-d9 dcl;propan-2-amine;hydrochloride;MFCD00050705;iso-Propyl-d7-amine;ISO-PROPYL-1,1,1,3,3,3-D6-AMINE HCL;1219798-50-1;ISOPROPYLAMINE HCl;PROPAN-2-AMINE HCL;ISOPROPYLAMINEHYDROCHLORIDE;DTXSID40884841;ISYORFGKSZLPNW-UHFFFAOYSA-N;2-Propanamine hydrochloride (1:1);propan-2-amine hydrochloric acid salt;AKOS027320903;2-Propanamine hydrochloride, AldrichCPR;AS-61678;SY107348;CS-0154205;FT-0611266;I0166;A883628

Chemical Property of Isopropylamine hydrochloride

Chemical Property:

• Vapor Pressure: 608mmHg at 25°C
• Melting Point: 160°C
• Boiling Point: 30.9°Cat760mmHg
• Flash Point: °C
• PSA: 26.02000
• Density: 0.719g/cm³
• LogP: 1.85580
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: Methanol (Slightly), Water
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 95.0501770
• Heavy Atom Count: 5
• Complexity: 10.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Isopropylamine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)N.Cl
• Uses: Isopropylamine Hydrochloride is an intermediate in the synthesis of 1-Cyano-3-isopropylguanidine (C955800).

Technology Process of Isopropylamine hydrochloride

There total 18 articles about Isopropylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

isopropylamine (75-31-0) → isopropylamine hydrochloride (15572-56-2)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; for 2h; Reflux;

DOI:10.1080/00397911.2015.1096943

Reference yield: 97.0%

2-nitropropane (79-46-9) → isopropylamine hydrochloride (15572-56-2)

Guidance literature:

2-nitropropane; With triethyl borane; potassium tert-butylate; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In tetrahydrofuran; at 100 ℃; for 24h; Inert atmosphere; Sealed tube; Green chemistry;

With hydrogenchloride; In water; at 20 ℃; for 6h; Green chemistry;

Reference yield: 96.7%

→ isopropylamine hydrochloride (15572-56-2)

Guidance literature:

upstream raw materials:

isopropylamine

ramifenazone

Diphenylphosphinsaeure-isopropylamid

N-Nitroso-N-isopropyl-1-methoxyethylamine

Downstream raw materials:

N,N-dimethylisopropyl amine

3-isopropylamino-1-phenyl-propan-1-one

1-isopropyl-4-phenyl-piperidin-4-ol

Isopropylamino-methylenaceton

Refernces

• 1、 Zhao, Lixing,Hu, Chenyang,Cong, Xuefeng,Deng, Gongda,Liu, Liu Leo,Luo, Meiming,Zeng, Xiaoming. "Cyclic (Alkyl)(amino)carbene Ligand-Promoted Nitro Deoxygenative Hydroboration with Chromium Catalysis: Scope, Mechanism, and Applications". supporting information. p. 1618 - 1629. Retrieved 2021/01/25.
• 2、 Gudun, Kristina A.,Hayrapetyan, Davit,Khalimon, Andrey Y.,Segizbayev, Medet,Slamova, Ainur,Zakarina, Raikhan. "Cobalt-Catalyzed Deoxygenative Hydroboration of Nitro Compounds and Applications to One-Pot Synthesis of Aldimines and Amides". . . Retrieved 2021/11/30.