Diphenylphosphinsaeure-isopropylamid

Base Information

• Chemical Name: Diphenylphosphinsaeure-isopropylamid
• CAS No.: 71847-21-7
• Molecular Formula: C₁₅H₁₈NOP
• Molecular Weight: 259.288
• Mol file: 71847-21-7.mol

Synonyms:Diphenylphosphinsaeure-isopropylamid

Chemical Property of Diphenylphosphinsaeure-isopropylamid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diphenylphosphinsaeure-isopropylamid

There total 10 articles about Diphenylphosphinsaeure-isopropylamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

isopropylamine (75-31-0) + Diphenylphosphinic chloride (1499-21-4) → Diphenylphosphinsaeure-isopropylamid (71847-21-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

DOI:10.1055/s-2007-967976

Reference yield: 86.0%

isopropylamine (75-31-0) + Diphenylphosphine oxide (4559-70-0) → Diphenylphosphinsaeure-isopropylamid (71847-21-7)

Guidance literature:

With chloroform; 1,8-diazabicyclo[5.4.0]undec-7-ene; at 25 ℃; for 3h;

DOI:10.1039/c9cc09407e

Reference yield: 60.0%

diphenylphosphinamide (5994-87-6) + isopropyl bromide (75-26-3) → Diphenylphosphinsaeure-isopropylamid (71847-21-7)

Guidance literature:

With sodium hydroxide; potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate; In benzene; Heating;

DOI:10.1055/s-1980-29184

upstream raw materials:

isopropylamine

Diphenylphosphinic chloride

diphenylphosphinamide

isopropyl alcohol

Downstream raw materials:

isopropylamine hydrochloride

diphenyl-phosphinic acid

isopropylamine

Refernces

• 1、 Han, Ya-Ping,Tan, Yushi,Yang, Shang-Dong,Zhang, Hong-Yu,Zhang, Yuecheng,Zhao, Jiquan. "Primary Amination of Ar2P(O)-H with (NH4)2CO3as an Ammonia Source under Simple and Mild Conditions and Its Extension to the Construction of Various P-N or P-O Bonds". . . Retrieved 2022/02/10.
• 2、 Fernández, Ignacio,Burgos, Pascual O?a,Gómez, Gloria Ruiz,Bled, Caroline,García-Granda, Santiago,Ortiz, Fernando López. "Phosphinamide-directed ortho metalations: Application to the desymmetrization of the diphenylphosphoryl group". . p. 611 - 614. Retrieved 2007/10/03.