2-AMINO-3-BROMOBENZOPHENONE

Base Information

• Chemical Name: 2-AMINO-3-BROMOBENZOPHENONE
• CAS No.: 808760-02-3
• Molecular Formula: C13H10BrNO
• Molecular Weight: 276.13
• Hs Code.: 2922399090
• Mol file: 808760-02-3.mol

Synonyms:Acetophenone,2-amino-3-bromo- (4CI);2-amino-3-bromobenzophenone;2-amino-3-bromophenyl phenyl ketone;

Chemical Property of 2-AMINO-3-BROMOBENZOPHENONE

Chemical Property:

• Boiling Point: 425.504 °C at 760 mmHg
• Flash Point: 211.138 °C
• PSA: 43.09000
• Density: 1.484 g/cm³
• LogP: 3.84350

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(2-Amino-3-bromophenyl)ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-3-BROMOBENZOPHENONE

There total 4 articles about 2-AMINO-3-BROMOBENZOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylmagnesium bromide (75-16-1) + 2-amino-3-bromo-benzonitrile (114344-60-4) → 1-(2-amino-3 -bromophenyl)ethanone (808760-02-3)

Guidance literature:

In tetrahydrofuran; at 0 ℃; Inert atmosphere;

Reference yield:

2-aminoacetophenone (551-93-9) → 1-(2-amino-5-bromophenyl)ethanone (29124-56-9) + 1-(2-amino-3 -bromophenyl)ethanone (808760-02-3)

Guidance literature:

With sodium perborate; ammonium heptamolybdate; potassium bromide; In acetic acid; at 20 ℃; for 2h;

DOI:10.1016/S0040-4039(00)00119-2

Reference yield:

2-aminoacetophenone (551-93-9) → 1-(2-amino-5-bromophenyl)ethanone (29124-56-9) + 1-(2-amino-3 -bromophenyl)ethanone (808760-02-3) + 1-(2-amino-3,5-dibromophenyl)ethanone (13445-89-1)

Guidance literature:

With sodium perborate; potassium bromide; In acetic acid; at 20 ℃; for 14h;

DOI:10.1016/S0040-4039(00)00119-2

upstream raw materials:

2-aminoacetophenone

methylmagnesium bromide

2-amino-3-bromo-benzonitrile

Downstream raw materials:

8-Brom-4-hydroxy-cinnolin

8-bromo-4-methyl-3-nitro-quinoline

N-(2-acetyl-6-bromo-phenyl)-3-(1-methyl-4-thiazol-2-yl-1H-imidazol-2-yl)-propionamide

Refernces

• 1、 Roche, Didier,Prasad, Kapa,Repic, Oljan,Blacklock, Thomas J.. "Mild and regioselective oxidative bromination of anilines using potassium bromide and sodium perborate". . p. 2083 - 2085. Retrieved 2007/10/03.