PYRIDINE-3,4,5-TRIAMINE

Base Information

• Chemical Name: PYRIDINE-3,4,5-TRIAMINE
• CAS No.: 618439-82-0
• Molecular Formula: C5H8 N4
• Molecular Weight: 124.145
• Hs Code.: 2933399090
• Mol file: 618439-82-0.mol

Synonyms:3,4,5-Pyridinetriamine

Chemical Property of PYRIDINE-3,4,5-TRIAMINE

Chemical Property:

• Vapor Pressure: 1.25E-09mmHg at 25°C
• Boiling Point: 486.8oC at 760 mmHg
• PKA: 9.08±0.24(Predicted)
• Flash Point: 280.1oC
• PSA: 90.95000
• Density: 1.387
• LogP: 1.57180
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99% ^*data from raw suppliers

3,4,5-Triaminopyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PYRIDINE-3,4,5-TRIAMINE

There total 4 articles about PYRIDINE-3,4,5-TRIAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-Amino-3,5-dinitropyridine (31793-29-0) → 3,4,5-triaminopyridine (618439-82-0)

Guidance literature:

With hydrogen; 10 wt% platinum on carbon; In ethanol; for 18h; under 2068.65 Torr;

Reference yield:

4-aminopyridine (504-24-5) → 3,4,5-triaminopyridine (618439-82-0)

Guidance literature:

Multi-step reaction with 3 steps

2: aqueous ammonium polysulfide

3: platinum; ethanol / Hydrogenation

With ammonium polysulfide; ethanol; platinum;

Reference yield:

3,4-diamino-5-nitropyridine (4318-68-7) → 3,4,5-triaminopyridine (618439-82-0)

Guidance literature:

With ethanol; platinum; Hydrogenation;

upstream raw materials:

3,4-diamino-5-nitropyridine

4-Amino-3,5-dinitropyridine

4-aminopyridine

Downstream raw materials:

8-amino-2-phenylpyrido[3,4-b]pyrazine

8-amino-2-(4-hydroxyphenyl)pyrido[3,4-b]pyrazine

8-amino-2,3-diphenylpyrido[3,4-b]pyrazine

8-amino-2,3-bis(4-methoxyphenyl)pyrido[3,4-b]pyrazine

Refernces

• 1、 Vera, Matthew D.,Lundquist IV, Joseph T.,Chengalvala, Murty V.,Cottom, Joshua E.,Feingold, Irene B.,Garrick, Lloyd M.,Green, Daniel M.,Hauze, Diane B.,Mann, Charles W.,Mehlmann, John F.,Rogers, John F.,Shanno, Linda,Wrobel, Jay E.,Pelletier, Jeffrey C.. "Synthesis and biological evaluation of piperazinyl heterocyclic antagonists of the gonadotropin releasing hormone (GnRH) receptor". supporting information; scheme or table. p. 2512 - 2515. Retrieved 2010/07/06.
• 2、 -. "Diaminopyridine compounds and methods of use". . . Retrieved 2008/06/13.